Results 21 to 30 of about 20,396 (218)

The Results of Re-certification of Reference Standard Sample Used for the Examination of Quality Smallpox Vaccines

Эпидемиология и вакцинопрофилактика, 2016
The article presents the results of research quality of drugs for the prevention of smallpox during the period from 2007 to 2015 years, where the reference standard uses industry standard of activity, specificity (identification) and necrotic activity of
A. V. Muhacheva, V. V. Perekrest, A. A. Movsesyants, K. A. Sarkisyan, A. U. Butyrskiy, O. V. Fadeikina, R. A. Volkova, D. V. Shvedov, V. A. Shevtsov   +8 more
doaj   +1 more source

Developing New Smallpox Vaccines

Emerging Infectious Diseases, 2001
New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments.
Steven R. Rosenthal, Michael Merchlinsky, Cynthia Kleppinger, Karen L. Goldenthal   +3 more
doaj   +1 more source

Trends of Pathogenicity and Potential Risk Evaluation of Central African Mpox Variant to Cause Global Public Health Emergency: A Cross-Sectional Analysis. [PDF]

Health Sci Rep
ABSTRACT Background With the re‐emergence of monkeypox (Mpox), it is vital for communities to assess and effectively respond to emerging outbreaks. This paper aims to review the potential of clade I Mpox to result in a widespread outbreak by assessing genetically enhanced virulence, transmission, and clinical manifestations.
Rahman MA, Kozlowich C, Katulka N, Thomas MR, Shanjana Y, Islam MR.   +5 more
europepmc   +2 more sources

Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox [PDF]

, 2012
Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid protection in a case of emergency ...
Gerd Sutter (181175), Majzoub Monir, Sutter Gerd, Kay-Martin Hanschmann (181170), Yasemin Suezer, Kalinke Ulrich, Suezer, Yasemin, Monir Majzoub (181167), Yasemin Suezer (181158), Hanschmann Kay-Martin, Theresa Frenz, Melanie Kremer (181155), Michael H. Lehmann (181173), Lehmann Michael H., Suezer Yasemin, Michael H. Lehmann, Volz Asisa, Asisa Volz (181161), Kay-Martin Hanschmann, Michael H Lehmann, Kremer, Melanie, Asisa Volz, Ulrich Kalinke, Hanschmann, Kay-Martin, Kremer Melanie, Kalinke, Ulrich, Theresa Frenz (181164), Monir Majzoub, Sutter, Gerd, Melanie Kremer, Frenz, Theresa, Ulrich Kalinke (41173), Frenz Theresa, Gerd Sutter, Lehmann, Michael H, Volz, Asisa, Majzoub, Monir, Lehmann, Michael H.   +37 more
core   +1 more source

Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence

Emerging Infectious Diseases, 2018
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre, Valentina Costantino, Xin Chen, Eva Segelov, Abrar Ahmad Chughtai, Anthony Kelleher, Mohana Kunasekaran, John Michael Lane   +7 more
doaj   +1 more source

Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design

Biomedicines, 2021
Various vaccinia virus (VACV) strains were applied during the smallpox vaccination campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV gained popularity as a viral vector thanks to increasing innovations in genetic ...
Onur Kaynarcalidan, Sara Moreno Mascaraque, Ingo Drexler   +2 more
doaj   +1 more source

Risks and Benefits of Preexposure and Postexposure Smallpox Vaccination

Emerging Infectious Diseases, 2003
This article presents a model and decision criteria for evaluating a person’s risk of pre- or postexposure smallpox vaccination in light of serious vaccine-related adverse events (death, postvaccine encephalitis and progressive vaccinia).
Martin I. Meltzer
doaj   +1 more source

The Pasteurian contribution to the history of vaccines

Comptes Rendus Biologies, 2022
Vaccination, the transmission of “vaccine”, a benign disease of cows, to immunize human beings against smallpox, was invented by Jenner at the end of the eighteenth century.
Schwartz, Maxime
doaj   +1 more source

Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks

Health Science Reports, 2022
Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam, Md. Jamal Hossain, Arpita Roy, A. H. M. Nazmul Hasan, Md. Ashrafur Rahman, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan   +6 more
doaj   +1 more source

A vaccinia virus renaissanceNew vaccine and immunotherapeutic uses after smallpox eradication

Human Vaccines & Immunotherapeutics, 2012
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi, Allison Titong, Caitlin J. Hagen   +2 more
doaj   +1 more source