Results 21 to 30 of about 18,470 (171)
The article presents the results of research quality of drugs for the prevention of smallpox during the period from 2007 to 2015 years, where the reference standard uses industry standard of activity, specificity (identification) and necrotic activity of
A. V. Muhacheva +8 more
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Developing New Smallpox Vaccines
New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments.
Steven R. Rosenthal +3 more
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Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design
Various vaccinia virus (VACV) strains were applied during the smallpox vaccination campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV gained popularity as a viral vector thanks to increasing innovations in genetic ...
Onur Kaynarcalidan +2 more
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Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre +7 more
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Risks and Benefits of Preexposure and Postexposure Smallpox Vaccination
This article presents a model and decision criteria for evaluating a person’s risk of pre- or postexposure smallpox vaccination in light of serious vaccine-related adverse events (death, postvaccine encephalitis and progressive vaccinia).
Martin I. Meltzer
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A vaccinia virus renaissance
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi +2 more
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The Pasteurian contribution to the history of vaccines
Vaccination, the transmission of “vaccine”, a benign disease of cows, to immunize human beings against smallpox, was invented by Jenner at the end of the eighteenth century.
Schwartz, Maxime
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Evolution of means and principles of smallpox vaccination
There are several possible reasons for the return of smallpox as an endemic disease. For example, the possibility of maintaining smallpox virus in an active state in the corpses of the dead, buried in permafrost regions, or the evolutionary changes of ...
S. V. Borisevich +7 more
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Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam +6 more
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In 1980, the World Health Assembly officially declared smallpox eradicated in the world, which allowed developed countries to stop preventive vaccination against this disease.
L. F. Stovba +4 more
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