Results 11 to 20 of about 38,009 (210)
Monkeypox vaccine – Current status
From a long time ago, there have been intermittent outbreaks of the zoonotic disease monkeypox (mpox) throughout Africa. The first case of human mpox was documented in 1970 in rural Congo. Mpox was classified as a Public Health Emergency of International
Brig Ambika Mohanty, Aroop Mohanty
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Smallpox is an acute contagious disease caused by the variola virus. According to WHO guidelines, the smallpox vaccine is administrated by scarification into the epidermis using a bifurcated needle moistened with a vaccine solution.
Sang-Gu Yim +11 more
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Immunomodulator-based enhancement of anti smallpox immune responses. [PDF]
BACKGROUND:The current live vaccinia virus vaccine used in the prevention of smallpox is contraindicated for millions of immune-compromised individuals. Although vaccination with the current smallpox vaccine produces protective immunity, it might result ...
Osmarie Martínez +9 more
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Human monkeypox represents a relatively underexplored infection that has received increased attention since the reported outbreak in May 2022. Due to its clinical similarities with human smallpox, this virus represents a potentially tremendous health ...
Dženan Kovačić, Adna Salihović
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Background Anthrax and smallpox are high-risk infectious diseases, and considered as potential agents for bioterrorism. To develop an effective countermeasure for these diseases, we constructed a bivalent vaccine against both anthrax and smallpox by ...
Deok Bum Park +9 more
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Prevention and Treatment of Monkeypox: A Systematic Review of Preclinical Studies
The outbreak of monkeypox, coupled with the onslaught of the COVID-19 pandemic is a critical communicable disease. This study aimed to systematically identify and review research done on preclinical studies focusing on the potential monkeypox treatment ...
Nurizzati Sudarmaji +5 more
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Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial [PDF]
BackgroundModified Vaccinia Ankara (MVA) is a live, viral vaccine under advanced development as a non-replicating smallpox vaccine. A randomised, double-blind, placebo-controlled phase III clinical trial was conducted to demonstrate the humoral ...
Chaplin, Paul +12 more
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The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG +6 more
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Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
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The article presents the results of research quality of drugs for the prevention of smallpox during the period from 2007 to 2015 years, where the reference standard uses industry standard of activity, specificity (identification) and necrotic activity of
A. V. Muhacheva +8 more
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