Results 11 to 20 of about 20,396 (218)

Low-Temperature Multiple Micro-Dispensing on Microneedles for Accurate Transcutaneous Smallpox Vaccination

open access: yesVaccines, 2022
Smallpox is an acute contagious disease caused by the variola virus. According to WHO guidelines, the smallpox vaccine is administrated by scarification into the epidermis using a bifurcated needle moistened with a vaccine solution.
Sang-Gu Yim   +11 more
doaj   +2 more sources

Monkeypox vaccine – Current status

open access: yesJournal of Integrative Medicine and Research, 2023
From a long time ago, there have been intermittent outbreaks of the zoonotic disease monkeypox (mpox) throughout Africa. The first case of human mpox was documented in 1970 in rural Congo. Mpox was classified as a Public Health Emergency of International
Brig Ambika Mohanty, Aroop Mohanty
doaj   +1 more source

Immunomodulator-based enhancement of anti smallpox immune responses. [PDF]

open access: yesPLoS ONE, 2015
BACKGROUND:The current live vaccinia virus vaccine used in the prevention of smallpox is contraindicated for millions of immune-compromised individuals. Although vaccination with the current smallpox vaccine produces protective immunity, it might result ...
Osmarie Martínez   +9 more
doaj   +1 more source

Construction of a bivalent vaccine against anthrax and smallpox using the attenuated vaccinia virus KVAC103

open access: yesBMC Microbiology, 2021
Background Anthrax and smallpox are high-risk infectious diseases, and considered as potential agents for bioterrorism. To develop an effective countermeasure for these diseases, we constructed a bivalent vaccine against both anthrax and smallpox by ...
Deok Bum Park   +9 more
doaj   +1 more source

Multi-epitope mRNA Vaccine Design that Exploits Variola Virus and Monkeypox Virus Proteins for Elicitation of Long-lasting Humoral and Cellular Protection Against Severe Disease

open access: yesJournal of Medical Science, 2022
Human monkeypox represents a relatively underexplored infection that has received increased attention since the reported outbreak in May 2022. Due to its clinical similarities with human smallpox, this virus represents a potentially tremendous health ...
Dženan Kovačić, Adna Salihović
doaj   +1 more source

Prevention and Treatment of Monkeypox: A Systematic Review of Preclinical Studies

open access: yesViruses, 2022
The outbreak of monkeypox, coupled with the onslaught of the COVID-19 pandemic is a critical communicable disease. This study aimed to systematically identify and review research done on preclinical studies focusing on the potential monkeypox treatment ...
Nurizzati Sudarmaji   +5 more
doaj   +1 more source

A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB   +6 more
europepmc   +2 more sources

Following in the footsteps of smallpox: can we achieve the global eradication of measles? [PDF]

open access: yes, 2004
BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths.
Morgan Oliver WC   +2 more
core   +1 more source

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections

open access: yesViruses, 2010
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj   +1 more source

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