Results 31 to 40 of about 361,909 (215)

Following in the footsteps of smallpox: can we achieve the global eradication of measles? [PDF]

open access: yes, 2004
BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths.
Morgan Oliver WC   +2 more
core   +2 more sources

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections

open access: yesViruses, 2010
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj   +1 more source

The Results of Re-certification of Reference Standard Sample Used for the Examination of Quality Smallpox Vaccines

open access: yesЭпидемиология и вакцинопрофилактика, 2016
The article presents the results of research quality of drugs for the prevention of smallpox during the period from 2007 to 2015 years, where the reference standard uses industry standard of activity, specificity (identification) and necrotic activity of
A. V. Muhacheva   +8 more
doaj   +1 more source

Developing New Smallpox Vaccines

open access: yesEmerging Infectious Diseases, 2001
New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments.
Steven R. Rosenthal   +3 more
doaj   +1 more source

Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox [PDF]

open access: yes, 2012
Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid protection in a case of emergency ...
Gerd Sutter (181175)   +37 more
core   +2 more sources

Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design

open access: yesBiomedicines, 2021
Various vaccinia virus (VACV) strains were applied during the smallpox vaccination campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV gained popularity as a viral vector thanks to increasing innovations in genetic ...
Onur Kaynarcalidan   +2 more
doaj   +1 more source

West Africa Smallpox/Measles Control Probram surveillance report [PDF]

open access: yes
Smallpox and yellow fever in West and West-Central Africa, 1940-1965: The tables and figures presented in this section of the Surveillance Report represent the best data available to the Smallpox Eradication Program at the present time regarding yellow ...

core   +4 more sources

Risks and Benefits of Preexposure and Postexposure Smallpox Vaccination

open access: yesEmerging Infectious Diseases, 2003
This article presents a model and decision criteria for evaluating a person’s risk of pre- or postexposure smallpox vaccination in light of serious vaccine-related adverse events (death, postvaccine encephalitis and progressive vaccinia).
Martin I. Meltzer
doaj   +1 more source

Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence

open access: yesEmerging Infectious Diseases, 2018
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre   +7 more
doaj   +1 more source

A vaccinia virus renaissanceNew vaccine and immunotherapeutic uses after smallpox eradication

open access: yesHuman Vaccines & Immunotherapeutics, 2012
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi   +2 more
doaj   +1 more source

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