Results 31 to 40 of about 20,396 (218)

Evolution of means and principles of smallpox vaccination

Вестник войск РХБ защиты, 2020
There are several possible reasons for the return of smallpox as an endemic disease. For example, the possibility of maintaining smallpox virus in an active state in the corpses of the dead, buried in permafrost regions, or the evolutionary changes of ...
S. V. Borisevich, V. N. Podkuyko, A. P. Pirozhkov, A. I. Terent'ev, V. P. Krasnyansky, E. V. Rozhdestvensky, S. V. Nazarov, S. V. Kuznecov   +7 more
doaj   +1 more source

A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity [PDF]

, 2012
© 2012 Elsevier Ltd. All rights reservedBackground: The development of a new, more effective vaccine against tuberculosis (TB) for use in healthy and HIV-infected adults, children and infants, remains a global health priority.
Minassian, Angela M, Porter, David W, Pathan, Ansar A, Rowland, Rosalind, Sander, C, Satti, Iman, Angela M Minassian, Nicola Williams, Lawrie, AM, Sander, Clare, Alison M Lawrie, Rowland, R, Poulton, ID, Rosalind Rowland, Brittain, N, Williams, Nicola, Pathan, AA, David W Porter, Minassian, AM, Helen McShane, Iman Satti, Ansar A Pathan, Ian D Poulton, Lawrie, Alison M, Nathaniel Brittain, Williams, N, Brittain, Nathaniel, Poulton, Ian D, Clare Sander, Porter, DW, Satti, I, McShane, H, McShane, Helen   +32 more
core   +1 more source

Safety and immunogenicity of IMVAMUNE®, a third-generation vaccine based on the modified vaccinia Ankara (MVA) strain

Биопрепараты: Профилактика, диагностика, лечение, 2023
In 1980, the World Health Assembly officially declared smallpox eradicated in the world, which allowed developed countries to stop preventive vaccination against this disease.
L. F. Stovba, O. V. Chukhralya, N. K. Chernikova, A. L. Khmelev, S. V. Borisevich   +4 more
doaj   +1 more source

Third-generation smallpox vaccines induce low-level cross-protecting neutralizing antibodies against Monkeypox virus in laboratory workers

Heliyon
Due to the discontinuation of routine smallpox vaccination after its eradication in 1980, a large part of the human population remains naïve against smallpox and other members of the orthopoxvirus genus.
Damian Jandrasits, Roland Züst, Denise Siegrist, Olivier B. Engler, Benjamin Weber, Kristina M. Schmidt, Hulda R. Jonsdottir   +6 more
doaj   +1 more source

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals

Nature Communications, 2023
In early 2022, a cluster of monkeypox virus (MPXV) infection (mpox) cases were identified within the UK with no prior travel history to MPXV-endemic regions.
Ashley D. Otter, Scott Jones, Bethany Hicks, Daniel Bailey, Helen Callaby, Catherine Houlihan, Tommy Rampling, Nicola Claire Gordon, Hannah Selman, Panayampalli S. Satheshkumar, Michael Townsend, Ravi Mehta, Marcus Pond, Rachael Jones, Deborah Wright, Clarissa Oeser, Simon Tonge, Ezra Linley, Georgia Hemingway, Tom Coleman, Sebastian Millward, Aaron Lloyd, Inger Damon, Tim Brooks, Richard Vipond, Cathy Rowe, Bassam Hallis   +26 more
doaj   +1 more source

The Global Monkeypox (Mpox) Outbreak: A Comprehensive Review

Vaccines, 2023
Monkeypox (Mpox) is a contagious illness that is caused by the monkeypox virus, which is part of the same family of viruses as variola, vaccinia, and cowpox.
Shriyansh Srivastava, Sachin Kumar, Shagun Jain, Aroop Mohanty, Neeraj Thapa, Prabhat Poudel, Krishna Bhusal, Zahraa Haleem Al-qaim, Joshuan J. Barboza, Bijaya Kumar Padhi, Ranjit Sah   +10 more
doaj   +1 more source

Targeting vaccination against novel infections : risk, age and spatial structure for pandemic influenza in Great Britain [PDF]

, 2011
The emergence of a novel strain of H1N1 influenza virus in Mexico in 2009, and its subsequent worldwide spread, has focused attention to the question of optimal deployment of mass vaccination campaigns.
White, Peter, Keeling, Matthew James
core   +1 more source

Remaining Questions about Clinical Variola Major

Emerging Infectious Diseases, 2011
After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
doaj   +1 more source

Non‐negative Gaussian estimation of variance components in random effects models

Canadian Journal of Statistics, EarlyView.
Abstract When used to estimate variance components (VCs), confidence intervals (CIs) can be truncated at zero, have a point estimate not in the quoted CI, be empty with positive probability, or be all‐inclusive. This is because they have conflicting dual roles, since they are considered to cover the parameter with a specified probability while also ...
André Plante, Michael Plante
wiley   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source