Following in the footsteps of smallpox: can we achieve the global eradication of measles? [PDF]
BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths.
Morgan Oliver WC +2 more
core +2 more sources
Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health.
Stuart N. Isaacs, Yuhong Xiao
doaj +1 more source
The article presents the results of research quality of drugs for the prevention of smallpox during the period from 2007 to 2015 years, where the reference standard uses industry standard of activity, specificity (identification) and necrotic activity of
A. V. Muhacheva +8 more
doaj +1 more source
Developing New Smallpox Vaccines
New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments.
Steven R. Rosenthal +3 more
doaj +1 more source
Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox [PDF]
Vaccination is highly effective in preventing various infectious diseases, whereas the constant threat of new emerging pathogens necessitates the development of innovative vaccination principles that also confer rapid protection in a case of emergency ...
Gerd Sutter (181175) +37 more
core +2 more sources
Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design
Various vaccinia virus (VACV) strains were applied during the smallpox vaccination campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV gained popularity as a viral vector thanks to increasing innovations in genetic ...
Onur Kaynarcalidan +2 more
doaj +1 more source
West Africa Smallpox/Measles Control Probram surveillance report [PDF]
Smallpox and yellow fever in West and West-Central Africa, 1940-1965: The tables and figures presented in this section of the Surveillance Report represent the best data available to the Smallpox Eradication Program at the present time regarding yellow ...
core +4 more sources
Risks and Benefits of Preexposure and Postexposure Smallpox Vaccination
This article presents a model and decision criteria for evaluating a person’s risk of pre- or postexposure smallpox vaccination in light of serious vaccine-related adverse events (death, postvaccine encephalitis and progressive vaccinia).
Martin I. Meltzer
doaj +1 more source
Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre +7 more
doaj +1 more source
A vaccinia virus renaissance
In 1796, Edward Jenner introduced the concept of vaccination with cowpox virus, an Orthopoxvirus within the family Poxviridae that elicits cross protective immunity against related orthopoxviruses, including smallpox virus (variola virus).
Paulo H. Verardi +2 more
doaj +1 more source

