Results 51 to 60 of about 18,470 (171)

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

Human monkeypox — After 40 years, an unintended consequence of smallpox eradication

Frontiers in Public Health, 2023
Monkeypox is one of the many zoonotic viruses that belong to the Orthopoxvirus genus of the Poxviridae family with a similar clinical appearance to smallpox. The symptoms of monkeypox include fever, headache, muscle aches, and lymphadenopathy.
Hussain Haider Shah, Muhammad Khizer Molani, Naqiha Shabbir   +2 more
doaj   +1 more source

Knowledge and Attitudes of Healthcare Workers Toward the Re‐Emergence of Human Monkeypox Virus Infection in Public Health Facilities in the Central Ethiopia Region: An Online Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Human monkeypox (mpox) is a re‐emerging zoonotic viral disease in Africa. Despite recent reports in Ethiopia, no studies have assessed healthcare workers' (HCWs) knowledge and attitudes in the Central Ethiopia Region. This study aimed to determine HCWs knowledge and attitudes toward the re‐emergence of mpox in public health
Yilma Markos Larebo, Zerfework Debebe Argago, Markos Selamu Jifar, Abebe Alemu Anshebo, Sujit Kumar Behera, Natarajan Gopalan   +5 more
wiley   +1 more source

The Role of Pharmacists in Tackling Mpox: Challenges and Future Prospects: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pharmacists play a key role in managing and mitigating mpox through clinical care, pharmacovigilance, vaccine management, and resilient supply chains. Management focuses on supportive care, infection prevention, and accurate diagnosis, with pharmacists ensuring the availability and rational use of vaccines, disinfectants ...
Ayalew Sirbemo Degebo, Fisseha Assegidew Gebretsadik, Abyou Seyfu Ambaye, Bedilu Linger Endalifer, Teshome Fentik Belachew   +4 more
wiley   +1 more source

Vaccines for preventing smallpox [PDF]

Cochrane Database of Systematic Reviews, 2004
Smallpox was eradicated by 1980, but its possible use as a bioweapon has rekindled interest in the development of protective vaccines. Therefore, stockpiled calf lymph-derived vaccines and recently developed cell-cultured vaccines have been investigated to contribute information to smallpox emergency response plans, while newer (non-replication ...
Metzger, W., Mordmüller, B.
openaire   +3 more sources

Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino, Marco Giuseppe Del Buono, Michele Marchetta, Nicola Potere, Aldo Bonaventura, Alessandra Vecchiè, Danilo Malandrino, Giacomo Emmi, Jordana Kron, Antonio Abbate   +9 more
wiley   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1310-1324, July 2026.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Correlations between Humoral Immunity, Vaccination Period and Demographic Characteristics of First Immunized Smallpox Vaccine Recipients

Эпидемиология и вакцинопрофилактика, 2020
Relevance. After vaccination against smallpox is completed, more than 50% of the population are not immune to pathogens of the genus Orthopoxvirus, which creates the risk of mass infection if the smallpox virus is used as a biological weapon.Aim.
O. S. Ermilova, Z. I. Ghinko, V. A. Belyavskaya   +2 more
doaj   +1 more source

Mpox Vaccination and Diagnosis Among Sexual and Gender Diverse Populations in Brazil: Results From a Large Nationwide Online Survey

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
ABSTRACT Introduction Since the onset of the 2022 multinational mpox outbreak, Brazil has reported one of the highest case burdens globally, disproportionately affecting sexual and gender diverse populations. Mpox vaccination efforts in Brazil have been limited by delayed procurement, restricted eligibility criteria and structural access barriers ...
Mayara Secco Torres Silva, Paula Mendes Luz, Carolina Coutinho, Brenda Hoagland, Emilia Moreira Jalil, Cristina Pimenta, Marcos Benedetti, Sandra Wagner Cardoso, Valdilea Gonçalves Veloso, Beatriz Grinsztejn, Thiago Silva Torres   +10 more
wiley   +1 more source

Durability of the Humoral Response to MPXV Infection

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
ABSTRACT Introduction Mpox virus (MPXV) re‐emerged in endemic countries in recent decades, resulting in large outbreaks in central and western Africa and a worldwide epidemic of clade IIb MPXV starting in 2022. Mpox cases in vaccinated persons, and a few documented reinfections, have raised questions about the durability of MPXV humoral immunity ...
Tara N. Palmore
wiley   +1 more source