Results 71 to 80 of about 361,909 (215)
Vaccines for preventing smallpox [PDF]
Smallpox was eradicated by 1980, but its possible use as a bioweapon has rekindled interest in the development of protective vaccines. Therefore, stockpiled calf lymph-derived vaccines and recently developed cell-cultured vaccines have been investigated to contribute information to smallpox emergency response plans, while newer (non-replication ...
Metzger, W., Mordmüller, B.
openaire +3 more sources
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman +6 more
wiley +1 more source
Can vaccinia virus be replaced by MVA virus for testing virucidal activity of chemical disinfectants? [PDF]
Background: Vaccinia virus strain Lister Elstree (VACV) is a test virus in the DVV/RKI guidelines as representative of the stable enveloped viruses.
Jochen Steinmann +8 more
core +2 more sources
Relevance. After vaccination against smallpox is completed, more than 50% of the population are not immune to pathogens of the genus Orthopoxvirus, which creates the risk of mass infection if the smallpox virus is used as a biological weapon.Aim.
O. S. Ermilova +2 more
doaj +1 more source
ABSTRACT Background and Aims Human monkeypox (mpox) is a re‐emerging zoonotic viral disease in Africa. Despite recent reports in Ethiopia, no studies have assessed healthcare workers' (HCWs) knowledge and attitudes in the Central Ethiopia Region. This study aimed to determine HCWs knowledge and attitudes toward the re‐emergence of mpox in public health
Yilma Markos Larebo +5 more
wiley +1 more source
The Immunogenetics of Smallpox Vaccination [PDF]
We hypothesized that individuals who develop fever after smallpox vaccination have genetically determined differences in their immune responses to vaccinia virus. We looked for an association between the development of fever and single-nucleotide polymorphisms (SNPs) in 19 candidate genes in 346 individuals previously assessed for clinical responses to
Samuel L, Stanley +9 more
openaire +2 more sources
Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
core +1 more source
Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino +9 more
wiley +1 more source
Who invented vaccination? [PDF]
Edward Jenner, whose ‘Inquiry’ (1798)1 was the first published report of vaccination against smallpox, is widely seen as the inventor of vaccination. However, other individuals could lay claim to this title, notably his contemporaries, Benjamin Jesty and
Jesty, R +2 more
core
The Influenza‐Specific Immunoglobulin Repertoire – Nimble Yet Steeped in Tradition
ABSTRACT Influenza virus has circulated in the human population and co‐evolved with us for centuries or longer, shaping our immune repertoires through a continuous host–virus arms race. Across individuals, antibodies repeatedly converge on shared solutions for capturing this shape‐shifting virus by precisely targeting conserved sites of vulnerability ...
Sarah F. Andrews, Masaru Kanekiyo
wiley +1 more source

