Results 11 to 20 of about 58,211 (212)

Smart drugs: implications for general practice. [PDF]

open access: yesBr J Gen Pract, 2017
The familiar landscape of substance misuse in the UK is changing. Recently a briefing in the BJGP highlighted two newer misuse scenarios: legal highs and ‘chemsex’.1 Another new misuse scenario generally escapes the attention of health professionals and others because it does not fit our concept of the term ‘recreational drugs’, since motivation for ...
Nicholson PJ, Wilson N.
europepmc   +4 more sources

Microneedles in Smart Drug Delivery

open access: yesAdvances in Wound Care, 2021
Significance: In biomedical setup, at large, and drug delivery, in particular, transdermal patches, hypodermal needles, and/or dermatological creams with the topical appliance are among the most widely practiced routes for transdermal drug delivery.
Muhammad Bilal   +5 more
openaire   +2 more sources

Smart Drugs: A Review

open access: yesInternational Journal for Innovation Education and Research, 2020
Smart drugs can change the way our mind functions. Smart drugs are also known as nootropics, which literally means the ability to bend or shape our mind. Smart drugs are classified into two main categories. They are classified based on their pharmacological action and their availability. The stimulant category of drugs is highly used and misused. There
Sahjesh Soni   +2 more
openaire   +2 more sources

Smart Nanovesicles for Drug Targeting and Delivery [PDF]

open access: yesPharmaceutics, 2019
Nanovesicles are highly-promising and versatile systems for the delivery and/or targeting of drugs, biomolecules and contrast agents [...]
Carlotta Marianecci, Maria Carafa
openaire   +4 more sources

Not so smart drugs [PDF]

open access: yesPsychiatric Bulletin, 1994
Dr Kwame McKenzie of the Institute of Psychiatry contrasts the publicity and the evidence behind drugs that are claimed to make us brighter.
openaire   +1 more source

Smart Responsive Microneedles for Controlled Drug Delivery

open access: yesMolecules, 2023
As an emerging technology, microneedles offer advantages such as painless administration, good biocompatibility, and ease of self-administration, so as to effectively treat various diseases, such as diabetes, wound repair, tumor treatment and so on.
Zhenzhen Qi   +4 more
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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