Results 31 to 40 of about 186,879 (245)

Morphology simulation of drop-on-demand inkjet-printed droplets

open access: yesnpj Flexible Electronics, 2022
Inkjet-printed electronics have become a popular research topic in recent years. For common drop-on-demand (DOD) inkjet printing technology, uneven edges are a universal problem.
Shaowei Hu   +3 more
doaj   +1 more source

Metformin Hydrochloride Significantly Inhibits Rotavirus Infection in Caco2 Cell Line, Intestinal Organoids, and Mice

open access: yesPharmaceuticals, 2023
Rotavirus is one of the main pathogens that causes severe diarrhea in children under the age of 5, primarily infecting the enterocytes of the small intestine.
Rui Zhang   +8 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Polymeric Hydrogels—A Promising Platform in Enhancing Water Security for a Sustainable Future

open access: yesAdvanced Materials Interfaces, 2021
Although water is essential for global health and the socio‐economic development of modern society, providing fresh water universally in a sustainable and affordable manner, for both developing and industrialized communities, is challenging.
Siew‐Leng Loo   +3 more
doaj   +1 more source

Droplet-Based Microfluidic Preparation of Shape-Variable Alginate Hydrogel Magnetic Micromotors

open access: yesNanomaterials, 2021
This article introduces a facile droplet-based microfluidic method for the preparation of Fe3O4-incorporated alginate hydrogel magnetic micromotors with variable shapes.
Cheng Zhang   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Snap evaporation of droplets on smooth topographies

open access: yesNature Communications, 2018
Droplet evaporation control has applications in inkjet printing and surface patterning. Here, the authors show that on slippery curved substrates droplets evaporate by slowly retracting and then suddenly snapping, which can be exploited to design ...
Gary G. Wells   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Influence of Tethered Ions on Electric Polarization and Electrorheological Property of Polymerized Ionic Liquids

open access: yesMolecules, 2020
Polymerized ionic liquids (PILs) show potential to be used as new water-free polyelectrolyte-based electrorheological (ER) material. To direct ER material design at the molecular level, unveiling structure-property relationships is essential. While a few
Fang He   +4 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

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