Results 141 to 150 of about 71,027 (265)

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li   +3 more
wiley   +1 more source

Ultrasound Characteristics of Twisted Pedunculated Subserosal Uterine Leiomyomas: A Case Report and a Systematic Review of the Literature

open access: yesJournal of Clinical Ultrasound, EarlyView.
Ultrasound may aid in the preoperative diagnosis of torsed pedunculated subserosal uterine leiomyomas (TPSUL), a rare but urgent condition. This study identifies consistent sonographic features across 42 cases, supporting ultrasound as a valuable diagnostic tool and highlighting the need for standardization in TPSUL imaging.
Maddalena Paoli   +5 more
wiley   +1 more source

Integrating Multiple Approaches to Reveal the Spatiotemporal Pattern of Soil Erosion in Mollisol Watershed

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Although numerous prediction methods have been developed, scientific estimation of the spatiotemporal pattern of soil erosion at the watershed scale remains challenging. In this study, fallout radionuclides of 210Pbex and 137Cs were used to estimate average annual soil erosion and deposition in a Mollisol watershed in Northeast China ...
Shaoliang Zhang   +7 more
wiley   +1 more source

FOXC1 Controls Smooth Muscle Cell Differentiation and Plasticity in Vascular Disease. [PDF]

open access: yesJACC Basic Transl Sci
Rykaczewska U   +18 more
europepmc   +1 more source

Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer

open access: yesMed Research, EarlyView.
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang   +4 more
wiley   +1 more source

Predictive Assessment of Progressive Damage in Mechanically Fastened Glass–Epoxy Composites

open access: yesPolymer Composites, EarlyView.
Progressive damage in mechanically fastened glass–epoxy composites. ABSTRACT Ensuring the structural integrity of advanced composites necessitates precise methodologies for forecasting the onset and progression of damage. This research focused on the predicting progressive damage (PD) for riveted joints composite laminates employing a combined ...
Nabi Mehri Khansari   +2 more
wiley   +1 more source

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