Results 31 to 40 of about 8,215,199 (301)

SMITH AT 300: ADAM SMITH ON EDINBURGH AND GLASGOW

open access: yesJournal of the History of Economic Thought, 2023
It is a difficult task to narrow down a favorite passage from a body of work as rich as that of Adam Smith. One of the things that has always amused me about Smith is his use of Scottish examples to make universal points. In one of these he launches himself into the long-running rivalry between Scotland’s two major cities: Edinburgh and Glasgow.
JHET Assistant, Craig Smith
openaire   +1 more source

Reference-free assembly of long-read transcriptome sequencing data with RNA-Bloom2

open access: yesNature Communications, 2023
Long-read sequencing technologies have improved significantly since their emergence. Their read lengths, potentially spanning entire transcripts, is advantageous for reconstructing transcriptomes.
Ka Ming Nip   +6 more
doaj   +1 more source

SMITH AT 300: ADAM SMITH AND THE IDEA OF “POLICE”

open access: yesJournal of the History of Economic Thought, 2023
“The more opulent therefore the society, labour will always be so much the dearer and work so much the cheaper, and if some opulent countries have lost several of their manufactures and some branches of their commerce by having been undersold in foreign markets by the traders and artisans of poorer countries, who were contented with less profit and ...
Alexandre Mendes Cunha, JHET Assistant
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

RResolver: efficient short-read repeat resolution within ABySS

open access: yesBMC Bioinformatics, 2022
Background De novo genome assembly is essential to modern genomics studies. As it is not biased by a reference, it is also a useful method for studying genomes with high variation, such as cancer genomes.
Vladimir Nikolić   +7 more
doaj   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth   +8 more
wiley   +1 more source

Systematic evaluation of isoform function in literature reports of alternative splicing

open access: yesBMC Genomics, 2018
Background Although most genes in mammalian genomes have multiple isoforms, an ongoing debate is whether these isoforms are all functional as well as the extent to which they increase the functional repertoire of the genome. To ground this debate in data,
Shamsuddin A. Bhuiyan   +7 more
doaj   +1 more source

Scandal in Scotland [PDF]

open access: yes, 2013
This paper examines the life and scandals of William Smith, born in Dyce, Scotland in 1882. In addition to the mystery surrounding the date of his own marriage and the birth of his first child, is Smith\u27s dalliance with his wife\u27s sister and the ...
Smith, Abigail
core   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Ali Smith interviewed by Caroline Smith [PDF]

open access: yes, 2007
Inverness-born Ali Smith’s first collection, Free Love and Other Stories (1995) was awarded Saltire Society Scottish First Book Of The Year Award. Her short stories and novels including the Man Booker Prize nominated Hotel World (2001) and 2005 winner of
Smith, Caroline
core  

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