Results 91 to 100 of about 55,907 (261)

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Modelisation and instrumentation of a mini UAV PEGASE [PDF]

, 2003
A Mini Unmanned Aerial Vehicle, PEGASE 50-4 developed at ENSICA, have been modelled and equipped with an embedded system in order to achieve a fully autonomous system. First, the global architecture of the PEGASE system is introduced.
Bordeneuve-Guibé, Joël, Briere, Yves, Parra, Camille, Su, Bingwei   +3 more
core  

Neural correlates of resilience to trauma during adolescence: A multi‐modal study

JCPP Advances, EarlyView.
Abstract Background Understanding resilience mechanisms is important for advancing early intervention strategies, yet research on the neurobiology of resilience in adolescents is limited. The present study examined the brain structural and resting‐state functional connectivity (rsFC) correlates of resilience to internalizing and externalizing symptoms ...
Lu Zhang, Vanessa L. Cropley, Divyangana Rakesh, Sarah Whittle   +3 more
wiley   +1 more source

The local time of a random walk on growing hypercubes [PDF]

, 2009
We study a random walk in a random environment (RWRE) on $\Z^d$, $1 \leq d < +\infty$. The main assumptions are that conditionned on the environment the random walk is reversible. Moreover we construct our environment in such a way that the walk can't be
Andreoletti, Pierre
core  

Data‐driven subtyping reveals heterogeneous functional brain development trajectories in preterm infants

Journal of Intelligent Medicine, EarlyView.
Abstract Brain development in preterm infants shows marked heterogeneity, often obscured by group‐level analyses. Between the group‐level and the individual difference, subgroup can model the heterogeneity of early developmental trajectories. To characterize this, we analyzed longitudinal functional connectome data from 90 preterm infants (scanned at ...
Jing Yu, Xinhao Wang, Weijin Liu, Rong Wang, Tianyu Fang, Yue Zhang, Xin Zhao, Yuanyuan Chen, Qiuyun Fan   +8 more
wiley   +1 more source

SMN Is Essential for the Biogenesis of U7 Small Nuclear Ribonucleoprotein and 3′-End Formation of Histone mRNAs

Cell Reports, 2013
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by a deficiency in the survival motor neuron (SMN) protein. SMN mediates the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs) and possibly other RNPs.
Sarah Tisdale, Francesco Lotti, Luciano Saieva, James P. Van Meerbeke, Thomas O. Crawford, Charlotte J. Sumner, George Z. Mentis, Livio Pellizzoni   +7 more
doaj   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

Arginine methylation-enabled FUS phase separation with SMN contributes to neuronal granule formation

Cell Reports
Summary: Various ribonucleoprotein complexes (RNPs) often function in the form of membraneless organelles derived from multivalence-driven liquid-liquid phase separation (LLPS).
Lingyao Wang, Pilong Li
doaj   +1 more source

Foraging and movement flexibility shape seed dispersal by an arboreal primate in a modified landscape

Oikos, EarlyView.
As habitats change, the effectiveness of animal‐mediated seed dispersal increasingly depends on animal responses to altered structure and resources. With habitat loss and degradation accelerating across the tropics, understanding how dispersers' foraging behavior and movement influence seed removal and deposition is critical to promoting forest ...
Anaid Cárdenas‐Navarrete, Sarie Van Belle, Onja H. Razafindratsima   +2 more
wiley   +1 more source

SEPARATE QUANTITATIVE PREDICTION OF OIL AND GAS CONTENT PROSPECTS FOR DZHEBOL STAGE PALEOZOIC DEPOSITS OF TIMAN-PECHORA OIL AND GAS BASIN

Известия высших учебных заведений: Нефть и газ, 2015
It is shown that the evolutionary-catagenetic model for calculating the initial potential hydrocarbon resources can serve as a scientific basis for the separate quantitative prediction of areas of oil-and-gas content.
A. I. Diyakonov, L. V. Parmuzina, S. V. Kochetov, A. Yu. Malikova   +3 more
doaj   +1 more source