Results 111 to 120 of about 12,623 (265)

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population‐Based Rhineland Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng, Konstantinos Melas, Santiago Estrada, N. Ahmad Aziz, Monique M. B. Breteler   +4 more
wiley   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

ApoE‐ and Cfh‐deficient mice exhibit structural and molecular features of human early–intermediate retinal degeneration

Animal Models and Experimental Medicine, EarlyView.
Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde, Maite Moreno Orduña, Jaione Bezunartea, Idoia Belza, Ainara Chas, Laura Fernández‐Sánchez, Nicolás Cuenca Navarro, Alfredo García‐Layana, Patricia Fernández‐Robredo, María Hernández   +9 more
wiley   +1 more source

Analysis of Consumer Satisfaction with the Quality of Smoked Fish Products at the Kenjeran Smoked Fish Center, Surabaya City

Grouper
Kenjeran is one of the coastal villages in the city of Surabaya. It is one of the coastal tourist attractions in Surabaya, famous as a center for smoked fish. The processing and marketing of smoked fish at the Kenjeran Smoked Fish Center still cannot be said to be hygienic and the sanitation aspect is still not taken into account, so it is necessary to
null Gilang Rusrita Aida, Angga Pratama Putra, Rosidah Wahyu Ningtyas, Didik Budiyanto, null Maria Erlinda Sarida, Filemon Cabrin Agun   +5 more
openaire   +1 more source

Thermal Black‐Infused Polyurethane Rigid Foams: Novel Formulations Toward Higher‐Performance and More Sustainable Insulation

Journal of Applied Polymer Science, EarlyView.
Thermal black improves polyurethane foam structure and stability. It helps the foam rise smoothly while promoting the formation of smaller, more uniform cells. The foam keeps its strength and insulation performance while reducing shrinkage. Its clean production and easy processing make it a sustainable, cost‐effective option for high‐performance ...
Mihaela Mihai, Adrien Faye, Sajjad Saeidlou, Edward Norton   +3 more
wiley   +1 more source

Interpreting a Legacy Fossil Assemblage Excavated From Waribruk (New Guinea II Cave), GunaiKurnai Aboriginal Country, Snowy River National Park, Southeastern Australia

Archaeology in Oceania, EarlyView.
ABSTRACT In this paper we report on faunal remains recovered from a legacy archaeological excavation undertaken in the rockshelter entrance of Waribruk (New Guinea II Cave), a GunaiKurnai site located on the west bank of the Snowy River, East Gippsland, southeastern Australia.
Matthew C. McDowell, Bruno David, Jean‐Jacques Delannoy, Russell Mullett, Fiona Petchey, Helen Green, Joanna Fresløv, GunaiKurnai Land and Waters Aboriginal Corporation   +7 more
wiley   +1 more source

Fish smoking and COPD: A fishy affair

Lung India, 2014
Sundeep Salvi, Bill Brashier
openaire   +3 more sources

Both Rerouted and In Situ Biceps Superior Capsular Reconstruction Augmentation During Arthroscopic Rotator Cuff Repair Improve Clinical Outcomes

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the clinical and radiologic outcomes at a 2‐year follow‐up of arthroscopic rotator cuff repair (RCR) augmented with superior capsular reconstruction (SCR) using the long head of the biceps tendon (LHBT) in patients with reparable posterosuperior rotator cuff tears.
Chang Hee Baek, Bo Taek Kim, Gustavo A. Gil Noriega, Jung Gon Kim, Chaemoon Lim, Paulo J. Llinás Hernández   +5 more
wiley   +1 more source