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Three-dimensional-mapping of smooth muscle morphogenesis in the vertebrate gastrointestinal tract [PDF]
Scientific ReportsGastrointestinal (GI) motility depends on smooth muscle contractions to propel contents through the digestive tract. GI muscle is organized into two perpendicular layers: the inner circular smooth muscle (CSM) and the outer longitudinal smooth muscle ...
Salomé Ruiz Demoulin +4 more
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Senescence as a Driver of Smooth Muscle Cell Plasticity and Atherosclerosis: Mechanisms and Therapeutic Opportunities [PDF]
CellsCell senescence is increasingly recognized as a key driver of atherosclerosis progression. Senescent smooth muscle cells (SMCs) lose their proliferative capacity and adopt a pro-inflammatory profile, contributing to impaired vessel repair and weakening ...
Lisa Steegen, Mandy O. J. Grootaert
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Physiological Reports, 2022 Penile detumescence is maintained by tonic contraction of corpus cavernosum smooth muscle cells (CCSMC), but the underlying mechanisms have not been fully elucidated.
Xin Rui Lim +4 more
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Arteriosclerosis, Thrombosis, and Vascular Biology, 2014 The prime function of the arterial smooth muscle cell (SMC) in adult individuals is to contract and relax, thereby regulating blood flow to target tissues. However, in several vascular diseases, arterial SMCs in the adult vessel undergo major changes in structure and function.
Valerie Z, Wall, Karin E, Bornfeldt
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Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice
Scientific Reports, 2022 Inhibition of Notch signaling in macrophages is known to reduce inflammation, however, its role in regulating vascular hyporeactivity in sepsis is unknown. Thus we aimed to evaluate the effect of sepsis on vascular Notch signaling.
Vandana Singh +8 more
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Role of smooth muscle progenitor cells in vascular mechanical injury and repair
Medicine in Novel Technology and Devices, 2022 Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong +7 more
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Characterization of Cecal Smooth Muscle Contraction in Laying Hens
Veterinary Sciences, 2021 The ceca play an important role in the physiology of the gastrointestinal tract in chickens. Nevertheless, there is a gap of knowledge regarding the functionality of the ceca in poultry, especially with respect to physiological cecal smooth muscle ...
Katrin Röhm +3 more
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Smooth muscle strips for intestinal tissue engineering. [PDF]
PLoS ONE, 2014 Functionally contracting smooth muscle is an essential part of the engineered intestine that has not been replicated in vitro. The purpose of this study is to produce contracting smooth muscle in culture by maintaining the native smooth muscle ...
Christopher M Walthers +3 more
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Defining smooth muscle cells and smooth muscle injury [PDF]
Journal of Clinical Investigation, 2005 For 3 decades, terms such as synthetic phenotype and contractile phenotype have been used to imply the existence of a specific mechanism for smooth muscle cell (SMC) responses to injury. In this issue of the JCI, Hendrix et al. offer a far more precise approach to examining the mechanisms of SMC responses to injury, focused not on general changes in ...
William M, Mahoney, Stephen M, Schwartz
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Majalah Obstetri dan Ginekologi, 2021 HIGHLIGHT 1. Pain intensity, smooth muscle cells density, and alpha-SMA expression can be used to analyze the role of smooth muscle in endometriosis. 2.
Sutrisno Sutrisno +2 more
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