Frontiers in Physiology, 2023 Exposure to hypoxia, due to high altitude or chronic lung disease, leads to structural changes in the pulmonary vascular wall, including hyperplasia and migration of pulmonary arterial smooth muscle cells (PASMCs).
Julie M. Lade +6 more
doaj +1 more source
Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]
, 2012 Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Reddy, M +10 more
core +1 more source
Vascular smooth muscle contraction in hypertension [PDF]
, 2018 Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia, and chronic kidney disease.
Aikaterini Anagnostopoulou +6 more
core +3 more sources
Herbal extracts modulate the amplitude and frequency of slow waves in circular smooth muscle of mouse small intestine [PDF]
, 2004 Background: Herbal preparations like STW 5 (Iberogast(R)) are widely used drugs in the treatment of dyspepsia and motility-related disorders of the gastrointestinal tract.
Weiser, D. +6 more
core +1 more source
Caveolin-3 promotes a vascular smooth muscle contractile phenotype
Frontiers in Cardiovascular Medicine, 2015 Epidemiological studies have demonstrated the importance of cardiovascular diseases in Western countries. Among the cell types associated with a dysfunctional vasculature, smooth muscle cells are believed to play an essential role in the development of ...
Jorge L. Gutierrez-Pajares +8 more
doaj +1 more source
The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
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Regulation of human airway smooth muscle cell migration and relevance to asthma
Respiratory Research, 2017 Airway remodelling is an important feature of asthma pathogenesis. A key structural change inherent in airway remodelling is increased airway smooth muscle mass.
Brittany Salter +4 more
doaj +1 more source
Smooth muscle raft-like membranes
Journal of Lipid Research, 2004 We developed a method for extracting raft-like, liquid-ordered membranes from the particulate fraction prepared from porcine trachealis smooth muscle.
Carl B. Baron, Ronald F. Coburn
doaj +1 more source
Highly effective non-viral gene transfer into vascular smooth muscle cells of cultured resistance arteries demonstrated by genetic inhibition of sphingosine-1-phosphate-induced vasoconstriction [PDF]
, 2003 The linkage of vascular genes to specific functions will lead to a better understanding of cardiovascular pathophysiology. We developed an experimental model that enables the introduction of one or multiple gene(s) into vascular smooth muscle cells ...
Pohl, U., Bolz, S. S.
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Orai store-operated Ca2+ entry channels modulate urethral smooth muscle contractility
ChannelsIn the European Union, urinary incontinence (UI) affects 45% of adults during their lifetime, representing a major clinical and socio-economic burden. Failure of urethral smooth muscle (USM) to contract normally (hypo or hypercontractility) contributes ...
Bernard T. Drumm, Neha Gupta
doaj +1 more source