Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]
, 2018 Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J +18 more
core +1 more source
A method for isolating smooth muscle cells from pig urinary bladder with low concentrations of collagenase and papain: the relation between calcium concentration and isolated cell length. [PDF]
, 1993 The present study describes a method for isolating single smooth muscle cells from pig urinary bladder using a continuous resuspension device. Low concentrations of collagenase and papain were sufficient to obtain a high yield of viable smooth muscle ...
Asselt, E. (Els) van +2 more
core +1 more source
Journal of the Formosan Medical Association, 2008 Myofibromas are well described in the head and neck region, but differentiating them from smooth muscle lesions is still difficult using smooth muscle immunohistochemical stains.
Julia Yu Fong Chang, Harvey P. Kessler
doaj +1 more source
Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts [PDF]
, 2019 © 2019 Published by Elsevier Inc.Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, inthe medial layer of the arteries.
Arnett, Timothy R +6 more
core +5 more sources
Frontiers in Physiology, 2014 The initial hypothesis was that the interstitial cells of Cajal (ICC) acted as obligatory intermediaries of enteric neurotransmission to smooth muscle cells. Much information for this hypothesis came from studies in W/Wv mice lacking ICC.
John H. Winston +4 more
doaj +1 more source
, 2005 Proliferation and migration of smooth muscle cells (SMCs) from the media towards the intima are key events in atherosclerosis and restenosis. During these processes, SMC undergo phenotypic modulations leading to SMC dedifferentiation. The identification and characterization of factors controlling these phenotypic changes are crucial in order to prevent
Bochaton-Piallat, Marie-Luce +1 more
openaire +3 more sources
Identification of Cells Expressing Cyclooxygenase-2 in Response to Interleukin-1β in Rat Aortae
Journal of Pharmacological Sciences, 2010 Localization of cyclooxygenase-2 (COX-2) in rat aortae was investigated. In endothelium-intact aortic strips stimulated with interleukin-1 β (IL-1 β ), COX-2 was detected in adventitial fibroblasts and macrophages but not in tunica media.
Tomoyuki Nakano, Ichiro Wakabayashi
doaj +1 more source
Mechanisms altering airway smooth muscle cell Ca(2+) homeostasis in two asthma models [PDF]
, 2008 Background: Asthma is characterized by airway remodeling, altered mucus production and airway smooth muscle cell (ASMC) contraction causing extensive airway narrowing. In particular, alterations of ASMC contractility seem to be of crucial importance. The
Bergner, Albrecht +6 more
core +1 more source
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. [PDF]
, 2012 Emerging evidence suggests that the T helper 17 (T(H)17) subset of αβ T cells contributes to the development of allergic asthma. In this study, we found that mice lacking the αvβ8 integrin on dendritic cells did not generate T(H)17 cells in the lung and ...
Atabai, Kamran +11 more
core +1 more source
Intercellular ultrafast Ca(2+) wave in vascular smooth muscle cells: numerical and experimental study. [PDF]
, 2016 Vascular smooth muscle cells exhibit intercellular Ca(2+) waves in response to local mechanical or KCl stimulation. Recently, a new type of intercellular Ca(2+) wave was observed in vitro in a linear arrangement of smooth muscle cells.
Meister, J.J. +4 more
core +1 more source