Results 21 to 30 of about 382,633 (219)

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching.

PLoS ONE, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Marcella Maddaluno, Gianluca Grassia, Maria Vittoria Di Lauro, Antonio Parisi, Francesco Maione, Carla Cicala, Daniele De Filippis, Teresa Iuvone, Angelo Guglielmotti, Pasquale Maffia, Nicola Mascolo, Armando Ialenti   +11 more
doaj   +1 more source

Epithelioid Leiomyoma of Uterus: A Case Report [PDF]

National Journal of Laboratory Medicine, 2016
Uterine smooth muscle tumours with distinctive epithelioid smooth muscle cells are called as epithelioid leiomyoma or leiomyoblastoma as the cells resemble smooth muscle cells of foetal uterus.
Chidambharam Choccalingam, Premila Samue, Shivakumaran Gurusamy   +2 more
doaj   +1 more source

Single-cell sequencing reveals PHLDA1-positive smooth muscle cells promote local invasion in head and neck squamous cell carcinoma

Translational Oncology
Background: Smooth muscle cells within the tumor microenvironment play a crucial role in cancer progression. However, their involvement in the local invasion of head and neck squamous cell carcinoma remains poorly understood.
Bing Guo, Xutao Wen, Shun Yu, Jun Yang
doaj   +1 more source

Outgrowing endothelial and smooth muscle cells for tissue engineering approaches

Journal of Tissue Engineering, 2017
In recent years, circulating progenitors of endothelial cells and smooth muscle cells were identified in the peripheral blood. In our study, we evaluated the utilization of both cell types isolated and differentiated from peripheral porcine blood in ...
Moritz Kolster, Mathias Wilhelmi, Claudia Schrimpf, Andres Hilfiker, Axel Haverich, Thomas Aper   +5 more
doaj   +1 more source

Lipoprotein lipase in atherosclerosis: its presence in smooth muscle cells and absence from macrophages

Journal of Lipid Research, 1987
The localization of lipoprotein lipase (LPL) in human atherosclerotic lesions was studied with immunocytochemical techniques. In the fibrous cap and surrounding intima of the plaque, where the smooth muscle cell is the dominating cell type, a high number
L Jonasson, G Bondjers, G K Hansson
doaj   +1 more source

Proteomic identification of ADAM12 as a regulator for TGF-β1-induced differentiation of human mesenchymal stem cells to smooth muscle cells. [PDF]

PLoS ONE, 2012
Transforming growth factor-β1 (TGF-β1) induces the differentiation of human adipose tissue-derived mesenchymal stem cells (hASCs) into smooth muscle cells. Lipid rafts are cholesterol-rich microdomains in cell membranes that reportedly play a key role in
Young Mi Kim, Jaeyoon Kim, Soon Chul Heo, Sang Hun Shin, Eun Kyoung Do, Dong-Soo Suh, Ki-Hyung Kim, Man-Soo Yoon, Taehoon G Lee, Jae Ho Kim   +9 more
doaj   +1 more source

Vinpocetine Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells. [PDF]

PLoS ONE, 2016
Vascular calcification is an active process of osteoblastic differentiation of vascular smooth muscle cells; however, its definite mechanism remains unknown.
Yun-Yun Ma, Lin Sun, Xiu-Juan Chen, Na Wang, Peng-Fei Yi, Min Song, Bo Zhang, Yu-Zhong Wang, Qiu-Hua Liang   +8 more
doaj   +1 more source

Arterial relaxation is coupled to inhibition of mitochondrial fission in arterial smooth muscle cells: comparison of vasorelaxant effects of verapamil and phentolamine

Acta Pharmaceutica Sinica B, 2017
Mitochondria are morphologically dynamic organelles which undergo fission and fusion processes. Our previous study found that arterial constriction was always accompanied by increased mitochondrial fission in smooth muscle cells, whereas inhibition of ...
Jing Jin, Xin Shen, Yu Tai, Shanliang Li, Mingyu Liu, Changlin Zhen, Xiuchen Xuan, Xiyue Zhang, Nan Hu, Xinzi Zhang, Deli Dong   +10 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Mechanisms of regulation electric and contractile activity smooth muscle cells: the role of cytoskeleton

Бюллетень сибирской медицины, 2008
The influence of modulation of cytoskeleton by colchicine, vinblastine, cytochalasine B and docetaxel on contractile reactions of smooth muscle cells caused by electric stimulus, depolarization, phenylephrine has been investigated by the mechanographical
M. A. Medvedev, M. B. Baskakov, S. V. Gusakova, I. V. Kovalyov, O. S. Melnik, V. V. Popov, L. V. Kapilevich   +6 more
doaj   +1 more source