Results 111 to 120 of about 29,989 (286)
Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots
Advanced Robotics Research, EarlyView.This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou +4 more
wiley +1 more source
Comparison of Finite Volume Method and Smoothed Particle Hydrodynamic in Modeling of Flow over Sharp-Crested Weir [PDF]
مهندسی منابع آب, 2018 This study presents a new hybrid algorithm for treating solid wall boundaries in the context of smoothed particle hydrodynamics (SPH) model. In this way, the basic concept is to fill an impervious region with some layers of dummy particles for improving ...
Ali Mahdavi, Hossein Khorshidi
doaj
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
Research on oil boom performance based on Smoothed Particle Hydrodynamics method. [PDF]
PLoS One, 2023 Liu J, Jiao P, Xu Y.
europepmc +1 more source
Advanced Science, EarlyView.The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang +10 more
wiley +1 more source
Resolving mixing in smoothed particle hydrodynamics [PDF]
, 2017 Standard formulations of smoothed particle hydrodynamics (SPH) are unable to resolve mixing at fluid boundaries. We use an error and stability analysis of the generalized SPH equations of motion to prove that this is due to two distinct problems.
Agertz, O., Hayfield, T., Read, J. I.
core
Advanced Science, EarlyView.We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin +10 more
wiley +1 more source
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Advances in Mechanical Engineering, 2018 In a Lagrangian meshfree particle-based method, the smoothing length determines the size of the support domain for each particle. Since the particle distribution is irregular and uneven in most cases, a fixed smoothing length sometime brings too much or ...
Sheng Wang, Yong Ou Zhang, Jing Ping Wu
doaj +1 more source