Results 121 to 130 of about 8,105 (305)

The Optimal Transportation Method in Solid Mechanics [PDF]

open access: yes, 2009
This dissertation is concerned with the development of a robust and efficient meshless method, the Optimal Transportation Method (OTM), for general solid flows involving extremely large deformation, fast, transient loading and hydrodynamic phenomena ...
Li, Bo
core   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

open access: yesAdvanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang   +10 more
wiley   +1 more source

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

open access: yesAdvanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang   +9 more
wiley   +1 more source

A discontinuous smooth particle hydrodynamics method for modeling deformation and failure processes of fractured rocks

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
A discontinuous smoothed particle hydrodynamics (DSPH) method considering block contacts is originally developed to model the cracking, frictional slip and large deformation in rock masses, and is verified by theoretical, numerical and/or experimental ...
Chengzhi Xia   +3 more
doaj   +1 more source

Comparison of Finite Volume Method and Smoothed Particle Hydrodynamic in Modeling of Flow over Sharp-Crested Weir [PDF]

open access: yesمهندسی منابع آب, 2018
This study presents a new hybrid algorithm for treating solid wall boundaries in the context of smoothed particle hydrodynamics (SPH) model. In this way, the basic concept is to fill an impervious region with some layers of dummy particles for improving ...
Ali Mahdavi, Hossein Khorshidi
doaj  

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

open access: yesAdvanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander   +14 more
wiley   +1 more source

A 3D Smoothed Particle Hydrodynamics Method with Reactive Flow Model for the Simulation of ANFO [PDF]

open access: yes, 2015
ANFO (ammonium nitrate/fuel oil) is a widely used bulk industrial explosive mixture that is considered to be highly non-ideal with long reaction zones, low detonation energies, and large failure diameters.
Wang, GY (reprint author), Univ Cincinnati, Sch Aerosp Syst, Cincinnati, OH 45221 USA.   +6 more
core   +1 more source

Mixing‐Driven Defects and Composition Evolution in Multi‐Material Metal Additive Manufacturing

open access: yesAdvanced Science, EarlyView.
Operando synchrotron X‐ray imaging coupled with high‐fidelity multiphysics modeling uncovers how inter‐material mixing reshapes keyhole dynamics and drives distinct pore‐formation pathways in multi‐material laser powder bed fusion (LPBF). Composition‐dependent instabilities trigger defects, whereas rescanning suppresses porosity and homogenizes Cu ...
Zhilang Zhang   +5 more
wiley   +1 more source

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