Results 131 to 140 of about 8,105 (305)

A new solid boundary treatment algorithm for smoothed particle hydrodynamics [PDF]

open access: yes, 2011
This paper presents a new solid boundary treatment algorithm for smoothed particle hydrodynamics (SPH). Two types of virtual particles are used to model the solid boundary, and information of the virtual particles can be obtained using enhanced SPH ...
Liu MB(刘谋斌)   +2 more
core  

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

open access: yesAdvanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li   +8 more
wiley   +1 more source

Smoothed particle hydrodynamics compared to finite volume methods in highly turbulent flow: a three-dimensional analysis of a marine propeller jet case [PDF]

open access: yes
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in D. Ferraro, J. M. Domínguez, A. Lauria, C. Altomare, F.
Domínguez Alonso, José Manuel   +4 more
core   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

open access: yesAdvanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian   +9 more
wiley   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

open access: yesAdvanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo   +5 more
wiley   +1 more source

Lagrangian meshfree finite difference particle method with variable smoothing length for solving wave equations

open access: yesAdvances in Mechanical Engineering, 2018
In a Lagrangian meshfree particle-based method, the smoothing length determines the size of the support domain for each particle. Since the particle distribution is irregular and uneven in most cases, a fixed smoothing length sometime brings too much or ...
Sheng Wang, Yong Ou Zhang, Jing Ping Wu
doaj   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

Adaptive Compressible Smoothed Particle Hydrodynamics

open access: yesJournal of Computational Physics
Modulating the number of particles in a region is key to accurately capturing the nuances in compressible flows with Smoothed Particle Hydrodynamics (SPH). This paper presents a volume-based adaptive refinement and derefinement procedure, with state-of-the-art features such as automatic local adaptivity and solution adaptivity applied in the context of
Navaneet Villodi, Prabhu Ramachandran
openaire   +2 more sources

Numerical Investigation of Fluid Mixing in a Micro-Channel Mixer with Two Rotating Stirrers by Using the Incompressible SPH Method [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2017
Fluid mixing is a crucial and challenging process for microfluidic systems, which are widely used in biochemical processes. Because of their fast performance, active micromixers that use stirrer blades are considered for biological applications.
Rahim Shamsoddini
doaj  

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