Results 251 to 260 of about 2,656,785 (305)

CMA-mediated USP9X degradation promotes SHH medulloblastoma progression by facilitating SUFU ubiquitination. [PDF]

Clin Transl Med
Gao B, Zhu Q, Kuang L, Li J, Meng Q, Han B, Wang Y, Zhang X, Zhang X, Wang X, Yu T, Yue S, Liu C.   +12 more
europepmc   +1 more source

When G Protein-Coupled Receptor Signaling Meets the Primary Cilium: Implications for Sonic Hedgehog Signaling. [PDF]

Bioessays
Kim SE.
europepmc   +1 more source

Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer. [PDF]

Cell Death Discov
Cong G, Zhu X, Chen XR, Chen H, Chong W.
europepmc   +1 more source

Most Promising Emerging Therapies for Pulmonary Fibrosis: Targeting Novel Pathways. [PDF]

Biomedicines
Carriera L, Lipsi R, Dodaj M, Inchingolo R, Smargiassi A, Coppola A, Mari PV, Barone R, Ielo S, Scala R, Richeldi L.   +10 more
europepmc   +1 more source

Disruption of primary ciliary prostaglandin E₂ signaling by transforming growth factor-β1 impairs endometrial receptivity. [PDF]

J Biomed Sci
Hou HT, Li WN, Lin TC, Lin CW, Pan PH, Lee CJ, Chen YC, Chen PF, Wang CY, Wu MH, Tsai SJ.   +10 more
europepmc   +1 more source

A Sonidegib Experience in the Treatment of Basal Cell Carcinoma with Systemic Lupus Erythematosus: A Case Report. [PDF]

Clin Cosmet Investig Dermatol
Shi L, Liu B, Gao P, Cao X, Wan C.
europepmc   +1 more source

Genetic Insight into Gorlin-Goltz Syndrome.

Indian J Dermatol
Madhu M.
europepmc   +1 more source

eLife Assessment: Multiple modes of cholesterol translocation in the human Smoothened receptor

openaire   +1 more source

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Inhibition of smoothened receptor by vismodegib leads to micrognathia during embryogenesis.

Differentiation, 2022
The mandible is an important part of the craniofacial skeleton. Mandibular development is complex and involves multiple signaling pathways. These signaling pathways participate in a complex regulatory mechanism to regulate mandibular growth. The function
Yandong Guo, Di Wu, Qingjiang Xu, Weihui Chen   +3 more
semanticscholar   +3 more sources

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

Nature, 1996
Members of the Hedgehog family of secreted proteins control a number of important inductive interactions in the development of both vertebrates and Drosophila, but little is known about the ways in which their signalling activities are transduced. In Drosophila, hedgehog is one of the segment-polarity genes, mutations of which disrupt the pattern and ...
M, van den Heuvel, P W, Ingham
openaire   +4 more sources