Results 81 to 90 of about 889,338 (324)

Acute Induced Pressure Overload Rapidly Incites Thoracic Aortic Aneurysmal Smooth Muscle Cell Phenotype [PDF]

open access: bronze, 2022
Albert J. Pedroza   +6 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Complexity-Regularized Regression for Serially-Correlated Residuals with Applications to Stock Market Data

open access: yesEntropy, 2014
A popular approach in the investigation of the short-term behavior of a non-stationary time series is to assume that the time series decomposes additively into a long-term trend and short-term fluctuations.
David Darmon, Michelle Girvan
doaj   +1 more source

Mechanism of Oxytocin-Induced Contraction in Rat Gastric Circular Smooth Muscle [PDF]

open access: gold, 2022
Mohammad Alqudah   +5 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Consistent estimation of the filtering and marginal smoothing distributions in nonparametric hidden Markov models [PDF]

open access: yes, 2015
In this paper, we consider the filtering and smoothing recursions in nonparametric finite state space hidden Markov models (HMMs) when the parameters of the model are unknown and replaced by estimators.
Corff, Sylvain Le   +2 more
core  

A Novel Method for Recognition of Persian Alphabet by Using Fuzzy Neural Network

open access: yesIEEE Access, 2018
This paper presents a system that can recognize handwritten words expressed using broken letters of the Persian alphabet. The proposed system can be used for most activities related to the gathering of public information.
Mohammad Mehdi Motahari Kia   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Time-Symmetric Quantum Theory of Smoothing

open access: yes, 2009
Smoothing is an estimation technique that takes into account both past and future observations, and can be more accurate than filtering alone. In this Letter, a quantum theory of smoothing is constructed using a time-symmetric formalism, thereby ...
A. H. Jazwinski   +11 more
core   +1 more source

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