Results 211 to 220 of about 243,728 (359)

A Prospective, Multicenter, Open Label Study Investigating the Implementation of a Standardized Algorithm for Coronary CaLcificatiOn With PlaquE Modification Using UltraSound Guidance to Improve Procedural and Clinical Outcomes (CYCLOPES): Design and Rationale of the CYCLOPES Trial

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Introduction Moderate‐to‐severe calcification is present in ~20%–30% of patients undergoing coronary angiography. Coronary lesion modification is often necessary to facilitate optimal stent delivery and expansion, with several dedicated devices now approved for calcium modification before stent implantation. The CYCLOPES study aims to evaluate
Daniel O'Callaghan, Rory Durand, Colm G. Hanratty, Thomas Cuisset, Beatriz Vaquerizo, Jan‐Malte Sinning, Peter O'Kane, J. J. Coughlan, Simon Walsh, Róisín Colleran, Himanshu Rai, Osama Soliman, Emanuele Barbato, Barbara E. Stähli, Robert A. Byrne   +14 more
wiley   +1 more source

Physicochemical Properties and Cross-Cultural Preference for Mushrooms Enriched Third-Generation Potato Snacks. [PDF]

Foods
Nemś A, Mora M, Rune CJB, Giacalone D, Noguera Artiaga L, Carbonell-Barrachina AA, Kolniak-Ostek J, Michalska-Ciechanowska A, Kita A.   +8 more
europepmc   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Canadian Professional Association Resources on Diet and Tooth Decay: Website Content Analysis. [PDF]

JMIR Form Res
Fotheringham M, Forbes LE, Papagerakis P, Lieffers J.   +3 more
europepmc   +1 more source

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans

Clinical Pharmacology &Therapeutics, EarlyView.
Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo, Outi Lapatto‐Reiniluoto, Mika Kurkela, Mikko Neuvonen, Eeva Moilanen, Mikko Niemi, Aleksi Tornio, Janne T. Backman   +7 more
wiley   +1 more source

Effects of Walnuts on Postprandial Cognitive Function in Adults With Subjective Cognitive Impairment: Protocol for a Randomized Crossover Trial.

JMIR Res Protoc
Zarich S, Cole RM, Fairchild K, Spakowicz D, Sparagna G, Madison A, Ni A, Belury MA.   +7 more
europepmc   +1 more source

Effects of Interoceptive and Exteroceptive Attention Training on Desire-Driven Eating in Healthy Adults: A Quasi-Experimental Early-Stage Feasibility Study. [PDF]

Foods
Frederiksen C, Byrne DV, Andersen BV.
europepmc   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Antioxidant, Antidiabetic, Anti-Obesity, and Anti-Inflammatory Activity of Tomato-Based Functional Snack Bars Enriched with Pea and RuBisCO Proteins. [PDF]

Foods
Tomassi E, Gabriele M, Sgalippa A, Gul MR, Tas O, Oztop MH, Pucci L.   +6 more
europepmc   +1 more source

Disentangling geography teacher educators' collective spaces of agency

The Curriculum Journal, EarlyView.
Abstract Societal trends such as increased accountability, teacher shortages, and flexibility in learning paths affect the work of teacher educators. This study explores the collective agency of Dutch geography teacher educators as they enact the subject pedagogy curriculum within this rapidly changing context.
Eefje Smit, Tine Béneker, Hanneke Tuithof   +2 more
wiley   +1 more source