The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition [PDF]
Oncogene, 2016 The transcription factor Snail is a master regulator of cellular identity and epithelial-to-mesenchymal transition (EMT) directly repressing a broad repertoire of epithelial genes.
Cecilia Battistelli +9 more
semanticscholar +4 more sources
The mitochondrial genome of the venomous cone snail conus consors [PDF]
, 2012 Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on ...
Baden-Tillson, Holly +9 more
core +14 more sources
Ocean Acidification Impedes Foraging Behavior in the Mud Snail Ilyanassa obsoleta
Journal of Marine Science and Engineering, 2023 Ocean acidification may diminish the response of many marine organisms to chemical cues that can be used to sense nearby food and predators, potentially altering community dynamics.
Maria Manz, Joshua Lord, Melissa Morales
doaj +1 more source
Release of Lungworm Larvae from Snails in the Environment: Potential for Alternative Transmission Pathways [PDF]
, 2015 Background: Gastropod-borne parasites may cause debilitating clinical conditions in animals and humans following the consumption of infected intermediate or paratenic hosts.
A Di Cesare +51 more
core +8 more sources
C-terminal domain small phosphatase-like 2 promotes epithelial-to-mesenchymal transition via Snail dephosphorylation and stabilization [PDF]
Open Biology, 2018 The epithelial-to-mesenchymal transition (EMT) is a cellular reprogramming process converting epithelial cells into mesenchymal cell morphology. Snail is a critical regulator of EMT by both suppressing epithelial gene expression and promoting mesenchymal
Yulan Zhao +3 more
doaj +1 more source
Theranostics, 2020 Rationale: Hepatocellular carcinoma (HCC) is one of the leading causes of mortality worldwide. Methyltransferase-like 3 (Mettl3), an RNA N6-methyladenosine (m6A) methyltransferase, has been shown to act as an oncogene in several human cancers.
Hongfa Xu +11 more
semanticscholar +1 more source
Frontiers in Neurology, 2017 Conventional microscopy has limitations in viewing the cochlear microstructures due to three-dimensional spiral structure and the overlying bone. But these issues can be overcome by imaging the cochlea in vitro with intravital multiphoton microscopy (MPM)
Hyun Mi Ju +10 more
doaj +1 more source
PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression [PDF]
, 2015 To overcome cancer cells resistance to pharmacological therapy, the development of new therapeutic approaches becomes urgent. For this purpose, the use of poly(ADP-ribose) polymerase (PARP) inhibitors in combination with other cytotoxic agents could ...
CAIAFA, Paola +11 more
core +2 more sources
Zhongliu Fangzhi Yanjiu, 2023 Objective To study the effect and mechanism of berberine (BBR) on the lung metastasis of mouse breast cancer via epithelial-mesenchymal transition (EMT).
YUAN Zhiying +5 more
doaj +1 more source
The Scaly-foot Snail genome and implications for the origins of biomineralised armour
Nature Communications, 2020 The Scaly-foot Snail, Chrysomallon squamiferum, presents a combination of biomineralised features, reminiscent of enigmatic early fossil taxa with complex shells and sclerites such as sachtids, but in a recently-diverged living species which even has ...
Jin Sun +20 more
semanticscholar +1 more source