Results 11 to 20 of about 118,470 (252)

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial-Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C-Dependent Stabilization of Snail mRNA. [PDF]

Adv Sci (Weinh)
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Zhao X, Yang L, Chen H, Guo C, Lu H, Zhu Y, Wang X, Li Y, Zhang R, Huang Z, Chen Y, Jin K, Xu Z, Meng L, Zhang L, Han Y, Yan Y, Kang Q, Wan J, Liu H.   +19 more
europepmc   +2 more sources

Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni [PDF]

, 2008
© 2008 Lockyer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Rollinson, D, Spinks, Jenny, Jennifer M Fitzpatrick, Hoffmann, Karl F, David Rollinson, Rollinson, David, Leslie R Noble, Lockyer, AE, Fitzpatrick, JM, Lockyer Anne E, Hoffmann, KF, Jenny Spinks, Hoffmann Karl F, Noble, Leslie R, Jones, Catherine S, Karl F Hoffmann, Noble, LR, Kane, RA, Catherine S Jones, Rollinson David, Anne E Lockyer, Jones, CS, Spinks, J, Fitzpatrick Jennifer M, Richard A Kane, Noble Leslie R, Lockyer, Anne E, Kane Richard A, Fitzpatrick, Jennifer M., Kane, Richard A., Spinks Jenny, Jones Catherine S   +31 more
core   +1 more source

An expressed sequence tag survey of gene expression in the pond snail Lymnaea stagnalis, an intermediate vector of Fasciola hepatica [PDF]

, 2005
The pond snail Lymnaea stagnalis is an intermediate vector for the liver fluke Fasciola hepatica, a common parasite of ruminants and humans. Yet, despite being a disease of medical and economic importance, as well as a potentially useful comparative tool,
Davison, A., Blaxter, M. L.
core   +1 more source

Snail Augments Nuclear Deformability to Promote Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma

Frontiers in Cell and Developmental Biology, 2022
Up to 50% of head and neck squamous cell carcinoma (HNSCC) patients have lymph node (LN) metastasis, resulting in poor survival rate. Numerous studies have supported the notion that the alterations of gene expression and mechanical properties of cancer ...
Yin-Quan Chen, Chen-Yu Hung, Ming-Tzo Wei, Jean-Cheng Kuo, Muh-Hwa Yang, Muh-Hwa Yang, Han-Ying Cheng, Arthur Chiou   +7 more
doaj   +1 more source

Selection on male and female reproductive traits in a simultaneous hermaphrodite land snail [PDF]

, 2013
Classical sexual selection theory assumes that the reproductive success of females is limited by the resources available for egg production, while the reproductive success of males is determined by the number of mates (Bateman’s principle).
Minoretti, Nicole
core   +1 more source

Parasitic influences on the host genome using the molluscan model organism biomphalaria glabrata [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The freshwater snail Biomphalaria glabrata is an intermediate host for Schistosoma mansoni parasites, causing one of the most prevalent parasitic infections
Arican-Goktas, Halime Derya
core   +7 more sources

Research Note: Genetic analysis, pathology, and vectors of echinostomiasis, a zoonotic helminth infection in chickens in Bangladesh

Poultry Science, 2022
: Echinostomes (Trematoda: Echinostomatidae) are food-borne zoonotic flatworms that affect birds, animals and humans, and has been classified as neglected tropical diseases (NTDs) by the World Health Organization (WHO), which cause severe enteritis in ...
Sharmin Shahid Labony, Sudip Paul, Md. Abdul Alim, Md. Shahadat Hossain, Takahiro Inoue, Sumaiya Naznin Ritu, Mohammad Zahangir Alam, Mahmudul Alam, Hayato Kawada, Muhammad Mehedi Hasan, Takeshi Hatta, Naotoshi Tsuji, Anisuzzaman   +12 more
doaj   +1 more source

Continuing Fragmentation of a Widespread Species by Geographical Barriers as Initial Step in a Land Snail Radiation on Crete [PDF]

, 2013
Sauer J, Oldeland J, Hausdorf B. Continuing Fragmentation of a Widespread Species by Geographical Barriers as Initial Step in a Land Snail Radiation on Crete. PLoS ONE.
Jens Oldel, Sauer Jan, Jens Oldeland, Hausdorf Bernhard, Jan Sauer, Oldeland Jens, Sauer, Jan, Hausdorf, Bernhard, Oldeland, Jens, Bernhard Hausdorf, Jan Sauer (408909), Bernhard Hausdorf (277904), Jens Oldeland (226793)   +12 more
core   +2 more sources

What explains the invading success of the aquatic mud snail Potamopyrgus antipodarum (Hydrobiidae, Mollusca)? [PDF]

, 2008
The spread of non-native species is one of the most harmful and least reversible disturbances in ecosystems. Species have to overcome several filters to become a pest (transport, establishment, spread and impact). Few studies have checked the traits that
Alonso, A., Castro-Diez, P.
core   +1 more source

Desempenho e características de carcaça do escargot francês (Helix aspersa maxima) alimentado com rações contendo diferentes óleos vegetais Performance and carcass characteristics of “gros gris” (Helix aspersa maxima) fed with different vegetable oils in diets

Ciência Rural, 2004
Objetivando avaliar a utilização de óleos vegetais de diferentes origens em rações no desempenho e características de carcaça do escargot francês “gros gris” (Helix aspersa maxima), 240 animais com peso inicial médio de 0,11g, foram ...
Carmino Hayashi, Claudemir Martins Soares, Makoto Matsushita, Eliana Maria Galdioli, Igor Consoni Cocito   +4 more
doaj   +1 more source