Results 51 to 60 of about 77,523 (237)
Advanced Science, EarlyView.Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen +11 more
wiley +1 more source
Advanced Science, EarlyView.Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source
Revista Portuguesa de Pneumologia, 2008 A aspiração de corpos estranhos é uma entidade frequente em crianças, mas rara em adultos. Os autores apresentam o caso de um adulto de 57 anos, sem comprometimento neurológico, que aspirou um caracol-das-vinhas (Helix pomatia) durante uma refeição ...
A. Santos Costa, Abel Afonso
doaj
Journal of Bioresource Management, 2020 The present study was conducted to study diversity and damage assessment of snails in cultivated crops and ornamental plants. The study revealed two types of snail species Macrochlamys indica and Indoplanorbis exustus in the study area. The sampled plots
Abu ul hassan faiz , Lariab Zahra Faiz
doaj +1 more source
Advanced Science, EarlyView.TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li +16 more
wiley +1 more source
Snail-Eating Snails of Florida, Gastropoda
EDIS, 2011 This document provides an overview of the snail-eating snails found in Florida, detailing three native and two introduced species. It highlights the identification, distribution, and habits of these predatory snails, including the well-known rosy wolfsnail (Euglandina rosea) and the decollate snail (Rumina decollata).
Kurt Auffenberg, Lionel Stange
openaire +3 more sources
Advanced Science, EarlyView.This study highlights the capacity for tumor suppressor SATB2 to recruit HDAC3 and catalyze histone H3K9 delactylation, thereby repress transcription of the oncogene LCN2. This novel epigenetic‐metabolic axis inhibits the growth and metastasis of non‐small cell lung cancer, delineating a new mechanistic pathway with potential therapeutic relevance ...
Ting Wen +10 more
wiley +1 more source
New species of stygobiotic Belgrandiella from north Bulgaria (Gastropoda: Hydrobiidae)
Biologica Nyssana, 2012 A new stygobiotic species of Belgrandiella from a cave in north Bulgaria was described. Nine shells were collected by the author on 09.03.2013 at the entrance of the Water cave (Vodnata) near village of Musina, north Bulgaria, N43 13 14.9 E25 25 39.6 ...
Georgiev, D.
doaj
Agricultura Tropica et Subtropica, 2018 Demand for Giant African Land Snail in Nigeria is so high such that it is very difficult to meet up with the supply as a protein source. However, during dry season, production at intensive level is often challenged with decline in growth and reproduction
Abiona John Adesanya +3 more
doaj +1 more source