Results 51 to 60 of about 151,928 (343)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Snail acetylation by autophagy‐derived acetyl‐coenzyme A promotes invasion and metastasis of KRAS‐LKB1 co‐mutated lung cancer cells

Cancer Communications, 2022
Background Autophagy is elevated in metastatic tumors and is often associated with active epithelial‐to‐mesenchymal transition (EMT). However, the extent to which EMT is dependent on autophagy is largely unknown.
Jang Hee Han, Yong Keon Kim, Hakhyun Kim, Jooyoung Lee, Myung Joon Oh, Sang Bum Kim, Minjee Kim, Kook Hwan Kim, Hyun Ju Yoon, Myung‐Shik Lee, John D. Minna, Michael A. White, Hyun Seok Kim   +12 more
doaj   +1 more source

Precision mapping of snail habitat provides a powerful indicator of human schistosomiasis transmission

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Schistosomiasis is a parasitic disease that affects ∼206 million people globally. The World Health Organization recently endorsed control of the freshwater snails that host schistosome infectious stages, and here, we show how to better ...
C. Wood, S. Sokolow, I. Jones, A. Chamberlin, K. Lafferty, A. Kuris, M. Jocqué, Skylar R. Hopkins, G. Adams, J. Buck, A. Lund, A. García-Vedrenne, E. Fiorenza, Jason Rohr, F. Allan, B. Webster, M. Rabone, J. Webster, Lydie Bandagny, R. Ndione, S. Senghor, A. Schacht, N. Jouanard, G. Riveau, G. D. De Leo   +24 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

The Black Consciousness Movement in South Africa: A Product of The Entire Black World

Historia Actual On-Line, 2009
El trabajo ilustra cómo el surgimiento del Movimiento de Conciencia Negra en Sudáfrica puede estar diametralmente unido a la emergencia de los movimientos de Conciencia Negra y Black Power en América.
Mgwebi Snail
doaj  

Lipids analysis in hemolymph of African giant Achatina fulica (Bowdich, 1822) exposed to different photoperiods

Brazilian Journal of Biology
The influence of different photophases (0, 6, 12, 18 and 24 hours) on the triglycerides and total cholesterol contents in the hemolymph of A. fulica was evaluated, since there is no information in the literature about the influence of this factor on ...
D. Lustrino, VM. Tunholi-Alves, VM. Tunholi, MP. Marassi, J. Pinheiro   +4 more
doaj   +1 more source

Type of cercaria in freshwater snails at Tunggu Pampang Reservoir, Makassar City, Indonesia

Инфекция и иммунитет, 2022
The Tunggu Pampang Reservoir is one of the reservoirs located in the city of Makassar. The functions of the reservoir area was tourist attractions and fish farming locations so that the local community uses them for swimming, fishing, selling, and ...
Arif Rahman Jabal, D. Mutiasari, H. Akbar, M. Arfah, M. Marhani, R. Rini, N. Sobak, A. J. Pisu, A. I. Toemon, A. Ratnasari   +9 more
doaj   +1 more source

Lichen Endozoochory by Snails

PLoS ONE, 2011
Endozoochory plays a prominent role for the dispersal of seed plants. However, for most other plant taxa it is not known whether this mode of dispersal occurs at all. Among those other taxa, lichens as symbiotic associations of algae and fungi are peculiar as their successful dispersal requires movement of propagules that leaves the symbiosis ...
Boch, Steffen, Prati, Daniel, Werth, Silke, Rüetschi, Jörg, Fischer, Markus   +4 more
openaire   +6 more sources

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source