Results 261 to 270 of about 143,736 (285)
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Drugs, 1997
Snake venoms are complex mixtures containing many different biologically active proteins and peptides. A number of these proteins act on components of the haemostatic system in humans. The paper focuses on those venom constituents that affect the blood coagulation pathway, endothelial cells and platelets. Several highly purified venom enzymes have been
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Snake venoms are complex mixtures containing many different biologically active proteins and peptides. A number of these proteins act on components of the haemostatic system in humans. The paper focuses on those venom constituents that affect the blood coagulation pathway, endothelial cells and platelets. Several highly purified venom enzymes have been
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Critical Reviews in Toxicology, 1999
Viperine and crotaline snake venoms contain one or more hemorrhagic principles called hemorrhagins. These are zinc-containing metalloproteases characterized by the presence of a protease domain, with additional domains in some of them. They act essentially by degrading the component proteins of basement membrane underlying capillary endothelial cells ...
Kunal Kumar Bhattacharyya +3 more
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Viperine and crotaline snake venoms contain one or more hemorrhagic principles called hemorrhagins. These are zinc-containing metalloproteases characterized by the presence of a protease domain, with additional domains in some of them. They act essentially by degrading the component proteins of basement membrane underlying capillary endothelial cells ...
Kunal Kumar Bhattacharyya +3 more
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Toxicon, 2005
Snakebite affects around 2.5 million humans annually, with greater than 100,000 deaths. Coagulopathy is a significant cause of both morbidity and mortality in these patients, either directly, or indirectly. This paper reviews clinical aspects of snakebite coagulopathy, including types of coagulopathy (procoagulant, fibrinogen clotting, fibrinolytic ...
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Snakebite affects around 2.5 million humans annually, with greater than 100,000 deaths. Coagulopathy is a significant cause of both morbidity and mortality in these patients, either directly, or indirectly. This paper reviews clinical aspects of snakebite coagulopathy, including types of coagulopathy (procoagulant, fibrinogen clotting, fibrinolytic ...
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Biotoxicology of sea snake venoms [PDF]
Annals of Emergency Medicine, 1987 Sea snakes are the most abundant venomous reptiles, found throughout the Indian and Pacific Oceans. Divided into two subfamilies, Laticaudinae and Hydrophiinae, all sea snakes are poisonous. Venoms are highly toxic, as indicated by low LD50 values in test animals. Toxic compounds include presynaptic and postsynaptic neurotoxins.
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Snake Venom: From Deadly Toxins to Life-saving Therapeutics.
Current Medicinal Chemistry, 2017Snakes are fascinating creatures and have been residents of this planet well before ancient humans dwelled the earth. Venomous snakes have been a figure of fear, and cause notable mortality throughout the world. The venom constitutes families of proteins
H. Waheed, S. F. Moin, M. Choudhary
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Current Pharmaceutical Biotechnology, 2018
BACKGROUND Research involving snake venom has gradually surpassed the simple discovery of new molecules using purification and structural characterization processes, and extended to the identification of their molecular targets and the evaluation of ...
R. Simões-Silva +13 more
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BACKGROUND Research involving snake venom has gradually surpassed the simple discovery of new molecules using purification and structural characterization processes, and extended to the identification of their molecular targets and the evaluation of ...
R. Simões-Silva +13 more
semanticscholar +1 more source
Snake Venoms and the Neuromuscular Junction
Seminars in Neurology, 2004There are approximately 420 venomous species of snakes living on the earth. Their venoms, each unique, can affect multiple organ systems. The venoms have a predilection for the peripheral nervous system where the neuromuscular junction is a favorite target.
Ludwig Gutmann, Robert L. Lewis
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Electrophoretic analysis of snake venoms
Journal of Chromatography B: Biomedical Sciences and Applications, 1992Electrophoretic analyses were conducted on snake venoms from 21 species representing Elapidae, Crotalidae and Viperidae. Denatured and native venoms were analyzed by polyacrylamide gel electrophoretic (PAGE) methods with sodium dodecyl sulfate (SDS) and without SDS.
T. Bhatti, C.E. C.-Mendoza, A.R. Bhatti
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Effects of Snake Venoms on Snakes
Copeia, 1946IN 1931 I started a series of experiments on snake venoms in order to procure comparative data on the effects of venoms on various species of snakes. The war brought the work to a standstill in 1941, after I had concluded 58 experiments. Although the small number of experiments does not permit definite conclusions to be drawn, the work is now ...
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JAMA: The Journal of the American Medical Association, 1984
It has been said that everyone knows how to build a fire, run a hotel, and coach a football team; "treat snakebite" could probably be added to that list. Everyone thinks he has the right answer. Those favoring surgical treatment view antivenin use as heretical at best, while proponents of antivenin use seem to believe that surgeons are remnants of an ...
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It has been said that everyone knows how to build a fire, run a hotel, and coach a football team; "treat snakebite" could probably be added to that list. Everyone thinks he has the right answer. Those favoring surgical treatment view antivenin use as heretical at best, while proponents of antivenin use seem to believe that surgeons are remnants of an ...
openaire +2 more sources