Results 61 to 70 of about 134,784 (231)

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

open access: yesAdvanced Science
The activation of NLRP3 inflammasome contributes to the development of numerous chronic inflammatory diseases, including ulcerative colitis and stress‐induced anxiety.
Wenbin Gai   +13 more
doaj   +1 more source

Anti-hemorrhagic effect of hydro-alcoholic extract of the leaves of Mikania glomerata in lesions induced by Bothrops jararaca venom in rats [PDF]

open access: yesActa Cirúrgica Brasileira, 2014
PURPOSE: To investigate the effects of hydroalcoholic leaf extract of Mikania glomerata Spreng (Asteraceae) on the activity of Bothrops jararaca snake venom in Wistar rats. METHODS: Fifty four rats Wistar were divided into six groups of nine animals
Vanessa Barreto Mourao   +9 more
doaj   +1 more source

A novel systematic approach for determining snake venom toxicity for next generation antivenom development

open access: yes, 2021
According to the World Health Organization statistics, it was estimated that in 2018 there were 81,000 138,000 new deaths world-wide reported for both men and women, due to snake envenomation.
Szteiter, Shelby
core  

Significant Far‐Right Challenges to Australian Society? The XYZ and AustraliaOne

open access: yesAustralian Journal of Politics &History, EarlyView.
ABSTRACT Scholars who analyse the Australian far‐right from a criminological or security studies perspective propose that activists and groups pose ‘political’ challenges to Australian society. This paper examines the far‐right news website The XYZ and the AustraliaOne political party, and argues that claims that the far‐right may normalise ...
Timothy Lynch
wiley   +1 more source

The Art of Anti-Snake Venom Administration in Snakebite Grade III Following Viper Snakebite in Developing Country: A Case Report

open access: yesJurnal Kedokteran Diponegoro
Snakebite remains a prior Neglected Tropical Disease in the World, especially in South-East Asia. There were many diversities in the management of snake bites based on the different levels of clinician experience.
Hapsari Kinanti, Agung Kusumanegara
doaj   +1 more source

Venomic Analysis of the Poorly Studied Desert Coral Snake, Micrurus tschudii tschudii, Supports the 3FTx/PLA2 Dichotomy across Micrurus Venoms

open access: yesToxins, 2016
The venom proteome of the poorly studied desert coral snake Micrurus tschudii tschudii was unveiled using a venomic approach, which identified ≥38 proteins belonging to only four snake venom protein families.
Libia Sanz   +7 more
doaj   +1 more source

Snake venom L-amino acid oxidases

open access: yes, 2002
L-amino acid oxidases are widely found in snake venoms and are thought to contribute to the toxicity upon envenomation. The mechanism of these toxic effects and whether they result from the enzymatic activity are still uncertain although many papers ...
Du, XY, Clemetson, KJ
core   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

Snake venom instability [PDF]

open access: yes, 2017
Comparative electrophoretic studies were conducted on the venom of the rinkals (Hemachatus haemachatus). Egyptian cobra Naja haje haje) and puffadder (Bills arietans).
Hattingh, J., Willemse, GT
core  

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

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