Results 41 to 50 of about 7,753 (187)

Development and Characterization of Anti-Naja ashei Three-Finger Toxins (3FTxs)-Specific Monoclonal Antibodies and Evaluation of Their In Vitro Inhibition Activity

Toxins, 2022
Antivenom immunotherapy is the mainstay of treatment for snakebite envenoming. Most parts of the world affected by snakebite envenoming depend on broad-spectrum polyspecific antivenoms that are known to contain a low content of case-specific efficacious ...
Ernest Z. Manson, Mutinda C. Kyama, Josephine Kimani, Aleksandra Bocian, Konrad K. Hus, Vladimír Petrilla, Jaroslav Legáth, James H. Kimotho   +7 more
doaj   +1 more source

Severe Snakebite Envenoming in Intensive Care [PDF]

Prague Medical Report, 2016
Snakebites by exotic venomous snakes can cause serious or even life-threatening envenoming. In Europe and North America most victims are breeders, with a few snakebites from wild native American rattlesnakes. The envenomed victims may present in organ and/or system failure with muscle paralysis, respiratory failure, circulatory instability, acute ...
Jiří Valenta, Zdeněk Stach, Pavel Michálek   +2 more
openaire   +3 more sources

Mapping the Risk of Snakebite in Sri Lanka - A National Survey with Geospatial Analysis.

PLoS Neglected Tropical Diseases, 2016
BackgroundThere is a paucity of robust epidemiological data on snakebite, and data available from hospitals and localized or time-limited surveys have major limitations. No study has investigated the incidence of snakebite across a whole country.
Dileepa Senajith Ediriweera, Anuradhani Kasturiratne, Arunasalam Pathmeswaran, Nipul Kithsiri Gunawardena, Buddhika Asiri Wijayawickrama, Shaluka Francis Jayamanne, Geoffrey Kennedy Isbister, Andrew Dawson, Emanuele Giorgi, Peter John Diggle, David Griffith Lalloo, Hithanadura Janaka de Silva   +11 more
doaj   +1 more source

Changes in serial laboratory test results in snakebite patients: when can we safely exclude envenoming?

, 2010
Objectives: To determine which laboratory tests are first associated with severe envenoming after a snakebite, when (ie, how long after the bite) the test results become abnormal, and whether this can determine a safe observation period after suspected ...
White, J., Brown, Simon A. G., Buckley, Nicholas, Buckley, N., Spain, David, Isbister, Geoffrey, Currie, B., Ireland, G., Brown, S., Stormer, J., Stormer, Jeff, Spain, D., Ireland, Graham, Currie, Bart, White, Julian, Isbister, G.   +15 more
core   +2 more sources

Paediatric snakebite envenoming: the world's most neglected 'Neglected Tropical Disease'? [PDF]

, 2020
Snakebite disproportionally affects children living in impoverished rural communities. The WHO has recently reinstated snakebites on its list of Neglected Tropical Diseases and launched a comprehensive Strategy for the Prevention and Control of Snakebite
Gustin, Rafael, Le Geyt, Jacqueline, Halbert, Jay, Ya, Kyaw Thu, Williams, David, Pach, Sophie, Avila-Agüero, María Luisa, Gutiérrez, José María, Habib, Abdulrazaq Garba, Maduwage, Kalana Prasad   +9 more
core   +2 more sources

Mortality after snakebite envenoming in children: a scoping review

, 2022
The objective of this scoping review is to assess the extent and type of evidence regarding risk factors for mortality after snakebite envenoming in ...
Lucy Guile, Adrienne Lee, José María Gutiérrez   +2 more
core   +1 more source

Compartment Syndrome following Bothrops Snakebite Leads to Decompressive Fasciotomies

Case Reports in Medicine, 2019
Snakebite envenoming is a neglected tropical disease with relevant morbidity and mortality. In this report, we illustrate the clinical course of a suspected Bothrops snakebite envenoming of a patient that evidenced severe pain, edema, pallor, regional ...
Murilo Sérgio Valente-Aguiar, Bruno Gonçalves da Costa e Silva, Teresa Magalhães, Ricardo Jorge Dinis-Oliveira   +3 more
doaj   +1 more source

Evaluating spatiotemporal dynamics of snakebite in Sri Lanka: Monthly incidence mapping from a national representative survey sample.

PLoS Neglected Tropical Diseases, 2021
BackgroundSnakebite incidence shows both spatial and temporal variation. However, no study has evaluated spatiotemporal patterns of snakebites across a country or region in detail.
Dileepa Senajith Ediriweera, Anuradhani Kasthuriratne, Arunasalam Pathmeswaran, Nipul Kithsiri Gunawardene, Shaluka Francis Jayamanne, Kris Murray, Takuya Iwamura, Geoffrey Isbister, Andrew Dawson, David Griffith Lalloo, Hithanadura Janaka de Silva, Peter John Diggle   +11 more
doaj   +1 more source

Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery

Advanced Science, Volume 13, Issue 53, 24 September 2026.
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le, P. Thien Phan, Lachlan Fitzgerald, P. Ross McAree, T. Nho Do, T. Thang Vo‐Doan   +5 more
wiley   +1 more source

Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom

Toxins, 2018
There is an unmet need for economical snakebite therapies with long shelf lives that are effective even with delays in treatment. The orally bioavailable, heat-stable, secretory phospholipase A2 (sPLA2) inhibitor, LY333013, demonstrates antidotal ...
Matthew R. Lewin, José María Gutiérrez, Stephen P. Samuel, María Herrera, Wendy Bryan-Quirós, Bruno Lomonte, Philip E. Bickler, Tommaso C. Bulfone, David J. Williams   +8 more
doaj   +1 more source