Results 51 to 60 of about 15,533,264 (179)

The Utility of Intranasal Corticosteroids in Association With Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis: A Real‐Life Multicenter Study by a Tuscany Group

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando   +17 more
wiley   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang   +16 more
wiley   +1 more source

Thai Translation and Validation of Chronic Rhinosinusitis‐Patient Reported Outcome (CRS‐PRO)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The Chronic Rhinosinusitis Patient‐Reported Outcome (CRS‐PRO) questionnaire was recently developed for use in chronic rhinosinusitis (CRS) patients. This instrument was developed using current diagnostic criteria. This study aimed to translate and validate CRS‐PRO for Thai CRS patients.
Wirach Chitsuthipakorn   +8 more
wiley   +1 more source

Silent Sinus Syndrome: 13‐Year Experience With Endoscopic Surgery and Long‐Term Patient Outcomes

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Silent sinus syndrome (SSS) is a rare condition characterized by spontaneous maxillary sinus collapse with associated orbital deformity. Existing studies are limited by heterogeneous surgical approaches, small sample sizes, and short follow‐up.
Sholem Hack   +3 more
wiley   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy   +2 more
wiley   +1 more source

Alterations in Nasal Function Following Total Laryngectomy and Their Clinical Correlates

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Although nasal structural and functional changes after total laryngectomy (TL) have been documented, the influence of clinical variables and symptoms remains underexplored. This study compared nasal structure and function between TL patients and healthy controls and identified clinical factors associated with these changes ...
Kajornpan Sermwittayawong   +3 more
wiley   +1 more source

The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti   +16 more
wiley   +1 more source

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