Results 41 to 50 of about 912,053 (206)
The advantages of SNP arrays over CGH arrays [PDF]
Molecular Cytogenetics, 2014 In recent years, with the rapid development of Chromosomal Micro-array Analysis (CMA), the resolution limit of 5Mb which was imposed by conventional cytogenetics, has been significantly lowered. Currently, array CGH is the most widely used CMA technology.
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Hybridization and amplification rate correction for affymetrix SNP arrays [PDF]
BMC Medical Genomics, 2012 Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation may be biased by several factors, including cross-hybridization and training sample batch,
Wang Quan +4 more
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BMC Bioinformatics, 2007 Background DNA copy number aberration (CNA) is one of the key characteristics of cancer cells. Recent studies demonstrated the feasibility of utilizing high density single nucleotide polymorphism (SNP) genotyping arrays to detect CNA.
Bailey Dione K +8 more
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QTL mapping of drought tolerance at germination stage in wheat using the 50 K SNP array
, 2021 Drought is a major concern among abiotic stresses in wheat (Triticum aestivum L.) production. Breeding resistant cultivars are the most effective means to manage drought stress.
Hongwei Geng +5 more
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A robust SNP barcode for typing Mycobacterium tuberculosis complex strains [PDF]
, 2014 Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance.
Glynn, Judith R. +29 more
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Development and validation of a 20K single nucleotide polymorphism (SNP) whole genome genotyping array for apple (Malus × domestica Borkh). [PDF]
PLoS ONE, 2014 High-density SNP arrays for genome-wide assessment of allelic variation have made high resolution genetic characterization of crop germplasm feasible. A medium density array for apple, the IRSC 8K SNP array, has been successfully developed and used for ...
Luca Bianco +14 more
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Molecular karyotyping using an SNP array for genomewide genotyping [PDF]
Journal of Medical Genetics, 2004 Background: Chromosomal imbalances are a major cause of developmental defects as well as cancer and often constitute the key in identification of novel disease related genes. Classical cytogenetic methods are limited in resolution and dependent on highly skilled labour, while methods with higher resolution, based on molecular ...
A, Rauch +8 more
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Identification of structural aberrations in cancer by SNP array analysis [PDF]
Genome Biology, 2007 Recent studies using single-nucleotide polymorphism arrays have pinpointed novel oncogenes and tumor suppressors involved in specific types of human cancers.
Heinrichs, Stefan, Look, A Thomas
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Visualization of genomic aberrations using Affymetrix SNP arrays [PDF]
Bioinformatics, 2006 AbstractMotivation: DNA copy number aberrations are frequently found in different types of cancer. Recent developments of microarray-based approaches have broadened the knowledge on number and structure of such aberrations. High-density single nucleotide polymorphism (SNP) microarrays provide an extremely high resolution with up to 500 000 SNPs per ...
André Müller +2 more
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