Mining Pure, Strict Epistatic Interactions from High-Dimensional Datasets: Ameliorating the Curse of Dimensionality [PDF]
, 2012 Background: The interaction between loci to affect phenotype is called epistasis. It is strict epistasis if no proper subset of the interacting loci exhibits a marginal effect.
Richard E. Neapolitan +2 more
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Serum cholesterol is a significant and independent mortality predictor in liver cirrhosis patients
Annals of Hepatology, 2013 Background and Aim. Accurate assessment of cirrhotic patient’s prognosis is essential for decisions regarding the course of treatment. Therefore we aimed to confirm and quantify the predictive value of serum cholesterol and serum triglycerides in liver ...
Martin Janičko +3 more
doaj +1 more source
Microarrays, 2016 The papers published in this Special Issue “SNP arrays” (Single Nucleotide Polymorphism Arrays) focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands
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SNP interaction pattern identifier (SIPI): an intensive search for SNP–SNP interaction patterns [PDF]
Bioinformatics, 2016 Abstract Motivation Testing SNP–SNP interactions is considered as a key for overcoming bottlenecks of genetic association studies. However, related statistical methods for testing SNP–SNP interactions are underdeveloped.
Lin, Hui-Yi +41 more
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Integrated probability of coronary heart disease subject to the -308 tumor necrosis factor-alpha SNP: a Bayesian meta-analysis [PDF]
, 2015 We present a meta-analysis of independent studies on the potential implication in the occurrence of coronary heart disease (CHD) of the single-nucleotide polymorphism (SNP) at the -308 position of the tumor necrosis factor alpha (TNF-alpha) gene.
Carvalho, C. Sofia
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Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation
Foods, 2021 Growing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to ...
Monika Kvakova +3 more
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Simulating Spiking Neural P systems without delays using GPUs [PDF]
, 2011 We present in this paper our work regarding simulating a type of P system known as a spiking neural P system (SNP system) using graphics processing units (GPUs). GPUs, because of their architectural optimization for parallel computations, are well-suited
Adorna, Henry +2 more
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Epidemiological risks of endoparasitoses spread by municipal waste water
Helminthologia, 2015 The occurrence of developmental stages of endoparasite germs (cysts, oocysts, protozoa, and helminth eggs) as an indirect detection factor of endoparasitoses circulation in the environment, was examined in raw municipal wastewater, sludge and ...
Dudlová A. +5 more
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SKM-SNP: SNP markers detection method
Journal of Biomedical Informatics, 2010 SKM-SNP, SNP markers detection program, is proposed to identify a set of relevant SNPs for the association between a disease and multiple marker genotypes. We employ a subspace categorical clustering algorithm to compute a weight for each SNP in the group of patient samples and the group of normal samples, and use the weights to identify the subsets of
Liu, Y +4 more
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Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]
, 2011 Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Koch, Alexander +9 more
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