Results 41 to 50 of about 400,356 (307)

When is an SNP not an SNP?

BioTechniques
Genomic duplications are important sources of structural change and gene innovation. In humans, the most recent and highly identical sequences (>90% homology, >1 kb long) are known as segmental duplications (SDs). Single-nucleotide variants or single-nucleotide polymorphisms within SDs have not been systematically assessed due to limitations around ...
Shapour Jalilzadeh, Valerie Walker, Gary P Leggatt, Eli Hatchwell   +3 more
openaire   +3 more sources

High Prevalence of Clostridioides difficile Ribotype 176 in the University Hospital in Kosice

Pathogens, 2023
Dysbiosis of the gut microbiota, caused by antibiotics, plays a key role in the establishment of Clostridioides difficile CD). Toxin-producing strains are involved in the pathogenesis of Clostridioides difficile infection (CDI), one of the most common ...
Katarina Curova, Martin Novotny, Lubos Ambro, Anna Kamlarova, Viera Lovayova, Vladimir Hrabovsky, Leonard Siegfried, Pavol Jarcuska, Peter Jarcuska, Annamaria Toporova   +9 more
doaj   +1 more source

Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans

, 2006
The identification of quantitative trait loci (QTLs) of small effect size that underlie complex traits poses a particular challenge for geneticists due to the large sample sizes and large numbers of genetic markers required for genomewide association ...
Plomin, R., Meaburn, Emma L., Leonard C. Schalkwyk, Robert Plomin, Emma Meaburn, Butcher, L.M., Plomin, R, Butcher, LM, Meaburn, E, Schalkwyk, LC, Schalkwyk, L.C., Butcher, L M, Schalkwyk, L C, Lee M. Butcher, Meaburn, EL   +14 more
core   +1 more source

SNP-SNP entropy-based interaction network of 11 ERAP1 SNPs in 748 Iranian BD patients.

, 2020
SNP-SNP entropy-based interaction network of 11 ERAP1 SNPs in 748 Iranian BD patients.
Parisa Riahi (8407764), Ali Javinani (5922311), Shayan Mostafaei (5478275), Akira Meguro (157086), Farhad Shahram (5478272), Amir Ashraf-Ganjouei (5500931), Anoshirvan Kazemnejad (6679151), Mahdi Mahmoudi (836542), Nobuhisa Mizuki (46911), Seyedeh Tahereh Faezi (8407767)   +9 more
core   +1 more source

SNP-based association analysis.

, 2022
The x-coordinate is the transcriptome length. A The results of the associations between SNPs and oleoresin yield. B The results of the associations between SNPs and Ht. C Associations between SNPs and DBH. D Associations between SNPs and ARW.
Shu Diao (126452), Qifu Luan (12035547), Xianyin Ding (12035544), Harry X. Wu (9649628), Jingmin Jiang (11981705), Yini Zhang (7045658)   +5 more
core   +1 more source

The development and characterization of a 60K SNP chip for chicken

, 2011
Background In livestock species like the chicken, high throughput single nucleotide polymorphism (SNP) genotyping assays are increasingly being used for whole genome association studies and as a tool in breeding (referred to as genomic selection).
Vereijken, Addie, Wesley C Warren, William M Muir, Hillier LaDeana W, LaDeana W Hillier, Zare Yalda, Groenen, Martien AM, Hillier, LaDeana W, Hans H Cheng, Groenen, Martin AM, Vereijken Addie, Muir William M, Zare, Yalda, Cheng, Hans H, Groenen Martien AM, Megens, H.J.W.C., Cheng Hans H, Megens Hendrik-Jan, Ron Okimoto, Vereijken, A., Muir, W.M., Martien AM Groenen, Groenen, M.A.M., Hendrik-Jan Megens, Warren Wesley C, Crooijmans, Richard PMA, Yalda Zare, Warren, W.C., Warren, Wesley C, Zare, Y., Okimoto Ron, Cheng, H.H., Richard PMA Crooijmans, Addie Vereijken, Hillier, L.W., Okimoto, Ron, Muir, Williams M, Crooijmans, R.P.M.A., Okimoto, R., Megens, Hendrik-Jan, Muir, William M, Crooijmans Richard PMA   +41 more
core   +1 more source

Proteomic Insight into Susac Syndrome Utilizing Tear Fluid—Case Study

Applied Sciences
Susac Syndrome (SuS) is a rare autoimmune neurovascular disorder characterized by sudden visual loss, hearing disturbances, and encephalopathy. Pathology affects the small vessels of the brain, retina, and inner ear.
Soňa Tkáčiková, Ivan Talian, Miroslav Marcin, Peter Bober, Tereza Ilavská, Simona Knížová, Miriama Turoková, Adriána Rašiová, Veronika Gibová, Vladimíra Tomečková   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Epidemiology of Primary Biliary Cholangitis in European Countries: A Systematic Review and Meta-Analysis

Canadian Journal of Gastroenterology and Hepatology, 2021
Background. Primary biliary cholangitis (PBC) is a chronic autoimmune cholestatic liver disease with wide ranges of reported incidence and prevalence. Aim. To map the incidence and prevalence of PBC in European countries from 2000 through 2020.
Jakub Gazda, Sylvia Drazilova, Martin Janicko, Peter Jarcuska   +3 more
doaj   +1 more source

Mesenchymal Stem Cells in the Treatment of Human Spinal Cord Injury: The Effect on Individual Values of pNF-H, GFAP, S100 Proteins and Selected Growth Factors, Cytokines and Chemokines

Current Issues in Molecular Biology, 2022
At present, there is no effective way to treat the consequences of spinal cord injury (SCI). SCI leads to the death of neural and glial cells and widespread neuroinflammation with persisting for several weeks after the injury.
Lucia Slovinska, Denisa Harvanova, Jana Janockova, Jana Matejova, Peter Cibur, Marko Moravek, Timea Spakova, Jan Rosocha   +7 more
doaj   +1 more source