Results 61 to 70 of about 434,626 (308)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

SNP-analysis.xlsx

, 2019
SNP analysis across ...
Mohammad Hamidian (2890205)
core   +1 more source

Virulence, phylogenetic background and antimicrobial resistance in Escherichia coli associated with extraintestinal infections

Journal of Infection and Public Health, 2020
Background: Escherichia coli (E. coli) is a major cause of urinary tract infections and bloodstream infections and an important agent in the resistance to antibiotics.
Katarína Čurová, Radka Slebodníková, Marta Kmeťová, Vladimír Hrabovský, Matúš Maruniak, Erika Liptáková, Leonard Siegfried   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Lower Viral Response to Pegylated Interferon Alpha 2a Treatment of Chronic Hepatitis B in Roma People in Eastern Slovakia

Gastroenterology Research and Practice, 2016
Aim. To evaluate the compliance and virological response to pegylated interferon alpha 2a treatment of chronic hepatitis B in Roma population compared to majority Caucasian population in Slovakia. Methods. Retrospective evaluation of a cohort of all Roma
Sylvia Drazilova, Martin Janicko, Pavol Kristian, Ivan Schreter, Branislav Kucinsky, Marek Kozlej, Ivana Hockickova, Peter Jarcuska   +7 more
doaj   +1 more source

No association between nest-box size and breeding parameters in White-throated Dipper (Cinclus cinclus) [PDF]

Tichodroma
Nest-box size itself may influence clutch size. In this study, we analysed the variation in clutch size and brood size (number of fledglings at ringing) in relation to nest-box size in the White-throated Dipper.
Miroslav Fulín, Michal Revický, Vladimír Kĺč, Vladimíra Kĺčová Kunštárová, Benjamín Jarčuška   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Specific Urinary Metabolites in Malignant Melanoma

Medicina, 2019
Background and objectives: Melanin, which has a confirmed role in melanoma cell behaviour, is formed in the process of melanogenesis and is synthesized from tryptophan, L-tyrosine and their metabolites.
Marcela Valko-Rokytovská, Beáta Hubková, Anna Birková, Jana Mašlanková, Marek Stupák, Marianna Zábavníková, Beáta Čižmárová, Mária Mareková   +7 more
doaj   +1 more source

The Epidemiology of Primary Biliary Cholangitis in European Countries: A Systematic Review and Meta-Analysis

Canadian Journal of Gastroenterology and Hepatology, 2021
Background. Primary biliary cholangitis (PBC) is a chronic autoimmune cholestatic liver disease with wide ranges of reported incidence and prevalence. Aim. To map the incidence and prevalence of PBC in European countries from 2000 through 2020.
Jakub Gazda, Sylvia Drazilova, Martin Janicko, Peter Jarcuska   +3 more
doaj   +1 more source

Mesenchymal Stem Cells in the Treatment of Human Spinal Cord Injury: The Effect on Individual Values of pNF-H, GFAP, S100 Proteins and Selected Growth Factors, Cytokines and Chemokines

Current Issues in Molecular Biology, 2022
At present, there is no effective way to treat the consequences of spinal cord injury (SCI). SCI leads to the death of neural and glial cells and widespread neuroinflammation with persisting for several weeks after the injury.
Lucia Slovinska, Denisa Harvanova, Jana Janockova, Jana Matejova, Peter Cibur, Marko Moravek, Timea Spakova, Jan Rosocha   +7 more
doaj   +1 more source