Results 71 to 80 of about 400,356 (307)

SNP-level pleiotropy counts and values for all biological and nuisance features used for analyses.

, 2023
SNP-level pleiotropy counts and values for all biological and nuisance features used for analyses.
Emily Yi (14822592), M. Cinta Romay (9467168), Anju Giri (11520266), Edward S. Buckler (8844038), Merritt Khaipho-Burch (11520269), Taylor Ferebee (14019209), Guillaume Ramstein (14349513), Brandon Monier (6336209)   +7 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Identification of a sex-linked SNP marker in the salmon louse (Lepeophtheirus salmonis) using RAD sequencing [PDF]

, 2013
The salmon louse (Lepeophtheirus salmonis (Krøyer, 1837)) is a parasitic copepod that can, if untreated, cause considerable damage to Atlantic salmon (Salmo salar Linnaeus, 1758) and incurs significant costs to the Atlantic salmon mariculture ...
Carmichael, Stephen N, Bassett, David I, Stephen N. Carmichael, Bron, James, Christie, Hayden R. L., Skern-Mauritzen, Rasmus, Bekaert, Michaël, David I Bassett, James E Bron, John B. Taggart (208020), Rasmus Skern-Mauritzen, Bassett, David I., Gharb, Karim, Skuce, Philip J, Taggart John B., Bron, James E., Bron, James E, Hayden R. L. Christie (471364), David I. Bassett (471365), Bekaert Michaël, Sturm, Armin, Carmichael Stephen N., Stephen N Carmichael, Taggart, John B, Bassett, D I, Sturm Armin, John B. Taggart, James E. Bron (308427), Gharbi Karim, Hayden R. L. Christie, Christie, Hayden R L, John B Taggart, Skuce, Philip J., Skern-Mauritzen Rasmus, Hayden R L Christie, Skuce Philip J., Michaël Bekaert, Armin Sturm, Philip J Skuce, Karim Gharbi (432878), Karim Gharbi, Philip J. Skuce, Philip J. Skuce (471366), Bassett David I., Skuce, Phillip, David I. Bassett, Stephen N. Carmichael (471363), Taggart, John, James E. Bron, Christie Hayden R. L., Taggart, John B., Rasmus Skern-Mauritzen (457732), Michaël Bekaert (121005), Carmichael, Stephen N., Armin Sturm (93476), Gharbi, Karim, Bron James E., Bakaert, Michaël   +57 more
core   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Oxidative Stress and the Nrf2/PPARγ Axis in the Endometrium: Insights into Female Fertility

Cells
Successful pregnancy depends on precise molecular regulation of uterine physiology, especially during the menstrual cycle. Deregulated oxidative stress (OS), often influenced by inflammatory changes but also by environmental factors, represents a ...
Peter Artimovič, Zuzana Badovská, Silvia Toporcerová, Ivana Špaková, Lukáš Smolko, Gabriela Sabolová, Eva Kriváková, Miroslava Rabajdová   +7 more
doaj   +1 more source

Magneto-optical imaging of the domain wall distortions enhanced by magnetic fields in amorphous glass-coated microwire

AIP Advances, 2023
Here, we employ time-resolved magneto-optical Kerr system (MOKE) imaging to ascertain the origin of domain wall motion in microwires. The MOKE visualisations of the domain walls motion on the surface of the microwires prove the domain wall pinning and ...
L. Fecova, R. Varga, K. Richter
doaj   +1 more source

Enhanced Terahertz Thermoelectricity Via Engineered Van Hove Singularities and Nernst Effect in Moiré Superlattices

Advanced Functional Materials, EarlyView.
Moiré band engineering in graphene/hexagonal boron nitride–based superlattices unlocks van Hove singularities (VHSs) for terahertz (THz) optoelectronics. Tuning the Fermi level near these singularities, associated with secondary neutrality points (SNPs), enhances the photothermoelectric response.
Leonid Elesin, Arthur L. Shilov, Subhajit Jana, Ilya Mazurenko, Pierre A. Pantaleon, Mikhail Kashchenko, Nikita Krivovichev, Viacheslav Dremov, Igor Gayduchenko, Takashi Taniguchi, Kenji Watanabe, Yibo Wang, Kostya S. Novoselov, Dmitry A. Svintsov, Grigory Goltsman, Elena I. Titova, Denis A. Bandurin   +16 more
wiley   +1 more source

SNP-index information of the three markers.

, 2016
SNP-index information of the three markers.
Yuanjun Ye (2872955), Ming Cai (342151), Huitang Pan (395889), Lu Feng (193271), Yiqian Ju (2872961), Qixiang Zhang (395887), Yao Jiao (2872958), Tangren Cheng (395888)   +7 more
core   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, Volume 13, Issue 31, 4 June 2026.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Pruritus, Fatigue, Osteoporosis and Dyslipoproteinemia in Pbc Patients: A Clinician’s Perspective

Gastroenterology Insights
In this review article, we summarize the most common clinical manifestations of Primary biliary cholangitis (PBC): pruritus, fatigue, osteoporosis, and dyslipoproteinemia and discuss their impact of the patients’ quality of life.
Sylvia Drazilova, Tomas Koky, Marian Macej, Martin Janicko, Dagmar Simkova, Ariunzaya Tsedendamba, Slavomira Komarova, Peter Jarcuska   +7 more
doaj   +1 more source