Results 71 to 80 of about 434,626 (308)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

SNP-SNP interaction models identified by the GMDR method with adjustment for age, gender, and education.

open access: yes, 2017
SNP-SNP interaction models identified by the GMDR method with adjustment for age, gender, and education.
Chung-Feng Kao (104445)   +6 more
core   +1 more source

Correction: Štofilová et al. Probiotic-Based Intervention in the Treatment of Ulcerative Colitis: Conventional and New Approaches. Biomedicines 2022, 10, 2236

open access: yesBiomedicines
The authors would like to add the following clarification regarding the clinical trials evaluating the probiotic product VSL#3 cited in the published paper [...]
Jana Štofilová   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

SNP-bis

open access: yes, 2012
SNP ...
Scotti-Saintagne, Caroline   +9 more
core   +1 more source

Application of massive parallel sequencing to whole genome SNP discovery in the porcine genome [PDF]

open access: yes, 2009
Background Although the Illumina 1 G Genome Analyzer generates billions of base pairs of sequence data, challenges arise in sequence selection due to the varying sequence quality.
Kerstens Hindrik HD   +24 more
core   +1 more source

SNP-level pleiotropy counts and values for all biological and nuisance features used for analyses.

open access: yes, 2023
SNP-level pleiotropy counts and values for all biological and nuisance features used for analyses.
Emily Yi (14822592)   +7 more
core   +1 more source

???????????????????????? SNP-?????????????? ?????? ???????????????????????????? ???????????????????? ?????????????????? ???????????????????????? ?????????????????? ?????????????????? ?? ??????????

open access: yes, 2021
Aims. The determination of the contribution of precursor populations into the genetic structure of modern inbreds accoding to the results of DNA single nucleotide polymorphism analysis. Methods. SNP-genotyping of 5 maize inbreds with GoldenGate test, Illumina VeraCode, Sentrix array matrice, BDI-III-pannel of 384 SNP-markers, computer analysis by ...
  +6 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Identification of a sex-linked SNP marker in the salmon louse (Lepeophtheirus salmonis) using RAD sequencing [PDF]

open access: yes, 2013
The salmon louse (Lepeophtheirus salmonis (Krøyer, 1837)) is a parasitic copepod that can, if untreated, cause considerable damage to Atlantic salmon (Salmo salar Linnaeus, 1758) and incurs significant costs to the Atlantic salmon mariculture ...
Carmichael, Stephen N   +57 more
core   +1 more source

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