Results 71 to 80 of about 444,550 (269)
ngs-snp-pipeline-v3.2
, 2012 nuclear locus assembly and SNP discovery pipeline R ...Peter H. Dutton (163010), Amy Frey (3261387), Archer, Frederick I., Hancock-Hanser, Brittany, Phillip A. Morin (198405), Frederick I. Archer (198398), Leslie, Matthew S., Dutton, Peter H., Matthew S. Leslie (370104), Morin, Phillip A., Brittany Hancock-Hanser (178889), Frey, Amy +11 morecore +1 more sourceGestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li +17 morewiley +1 more sourceA Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing
Advanced Science, EarlyView.A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang +18 morewiley +1 more sourcePruritus, Fatigue, Osteoporosis and Dyslipoproteinemia in Pbc Patients: A Clinician’s Perspective
Gastroenterology InsightsIn this review article, we summarize the most common clinical manifestations of Primary biliary cholangitis (PBC): pruritus, fatigue, osteoporosis, and dyslipoproteinemia and discuss their impact of the patients’ quality of life.Sylvia Drazilova, Tomas Koky, Marian Macej, Martin Janicko, Dagmar Simkova, Ariunzaya Tsedendamba, Slavomira Komarova, Peter Jarcuska +7 moredoaj +1 more sourceSource code for snp-dists software
, 2018 This tar.gz file contains the source code, test data, and documentation for snp-dists, a bioinformatics command line tool for calculating SNP distance matrix from a FASTA multiple sequence alignment.Seemann, Torsten, Seemann, Torsten (5288968) +1 morecore +1 more sourceGenome wide SNP discovery, analysis and evaluation in mallard (Anas platyrhynchos) [PDF]
, 2011 Background Next generation sequencing technologies allow to obtain at low cost the genomic sequence information that currently lacks for most economically and ecologically important organisms. For the mallard duck genomic data is limited. The mallard is, Kerstens Hindrik HD, Prins, Herbert HT, Robert HS Kraus, van Hooft, Pim, Kraus, R.H.S., Prins, Herbert H. T., Prins, H.H.T., Poel, J., Van Hooft Pim, Hooft, Pim Van, Li Ning, Jan J Van Der Poel, Johan Elmberg, Huang Yinhua, Prins Herbert HT, Elmberg, Johan, Vignal Alain, Martien AM Groenen, Crooijmans, Richard P. M. A., Elmberg Johan, Groenen, M.A.M., van Hooft, Pim,, Van Der Poel Jan J, Huang, Y., Kraus, Robert Hs, Pim Van Hooft, Vignal, Alain, Crooijmans, R.P.M.A., Yinhua Huang, Groenen, Martien A. M., Vignal, Alain,, Li, N., Crooijmans, R., Kerstens, H., Crooijmans, Richard P. M. A.,, Herbert HT Prins, Elmberg, J., Groenen, M., Kerstens, Hindrik HD, Elmberg, Johan,, Kraus, Robert, Groenen, Martien AM, Prins, Herbert H. T.,, Kraus Robert HS, Prins, H., Huang, Yinhua,, Groenen Martien AM, Poel, J.J., van der, Kersten, H.H.D., van der Poel, Jan J., Li, Ning, Kraus, Robert H. S.,, Kraus, Robert H. S., Huang, Yinhua, Hooft, W.F., van, Crooijmans, Richard PMA, Kerstens, Hindrik H. D.,, Kerstens, Hindrik H. D., Li, Ning,, Hooft, P., Hindrik HD Kerstens, Richard PMA Crooijmans, Vignal, A., Alain Vignal, Kraus, R., Groenen, Martien A. M.,, Ning Li, Crooijmans Richard PMA, van der Poel, Jan J., +68 morecore +2 more sourcesThe Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit
Advanced Science, EarlyView.This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu +9 morewiley +1 more sourceExtent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel [PDF]
, 2008 BACKGROUND: The extent of linkage disequilibrium (LD) within a population determines the number of markers that will be required for successful association mapping and marker-assisted selection.Andrew R Collins, Zenger, Kyall R., Jeremy F Taylor, Zenger Kyall R, Frank W Nicholas, Cavanagh Julie AL, Taylor, Jeremy F., Barris Wes, Wes Barris, Taylor Jeremy F, Kyall R Zenger, Barris, Wes, Nicholas, Frank W., Julie AL Cavanagh, Schnabel Robert D, Collins, Andrew R., Raadsma Herman W, Raadsma, Herman W., Nicholas Frank W, Herman W Raadsma, Khatkar, Mehar S., Khatkar Mehar S, Collins Andrew R, Nicholas, Mehar S., Cavanagh, Julie A.L., Robert D Schnabel, Mehar S Khatkar, Schnabel, Robert D. +27 morecore +1 more sourceConditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L
Advanced Science, EarlyView.Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang +12 morewiley +1 more sourceIdentification of a sex-linked SNP marker in the salmon louse (Lepeophtheirus salmonis) using RAD sequencing [PDF]
, 2013 The salmon louse (Lepeophtheirus salmonis (Krøyer, 1837)) is a parasitic copepod that can, if untreated, cause considerable damage to Atlantic salmon (Salmo salar Linnaeus, 1758) and incurs significant costs to the Atlantic salmon mariculture ...Carmichael, Stephen N, Bassett, David I, Stephen N. Carmichael, Bron, James, Christie, Hayden R. L., Skern-Mauritzen, Rasmus, Bekaert, Michaël, David I Bassett, James E Bron, John B. Taggart (208020), Rasmus Skern-Mauritzen, Bassett, David I., Gharb, Karim, Skuce, Philip J, Taggart John B., Bron, James E., Bron, James E, Hayden R. L. Christie (471364), David I. Bassett (471365), Bekaert Michaël, Sturm, Armin, Carmichael Stephen N., Stephen N Carmichael, Taggart, John B, Bassett, D I, Sturm Armin, John B. Taggart, James E. Bron (308427), Gharbi Karim, Hayden R. L. Christie, Christie, Hayden R L, John B Taggart, Skuce, Philip J., Skern-Mauritzen Rasmus, Hayden R L Christie, Skuce Philip J., Michaël Bekaert, Armin Sturm, Philip J Skuce, Karim Gharbi (432878), Karim Gharbi, Philip J. Skuce, Philip J. Skuce (471366), Bassett David I., Skuce, Phillip, David I. Bassett, Stephen N. Carmichael (471363), Taggart, John, James E. Bron, Christie Hayden R. L., Taggart, John B., Rasmus Skern-Mauritzen (457732), Michaël Bekaert (121005), Carmichael, Stephen N., Armin Sturm (93476), Gharbi, Karim, Bron James E., Bakaert, Michaël, Taggart, J.B., Bassett, D.I., Carmichael, S.N., Skern-Mauritzen, R., Bron, J.E., Skuce, P.J., Sturm, A., Gharbi, K., Bekaert, M., Christie, H.R.L. +67 morecore +1 more source
