Results 251 to 260 of about 23,427,651 (311)

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

JCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser, Wangjingyi Liao, Andrea G. Allegrini, Kaili Rimfeld, Thalia C. Eley, Robert Plomin, Margherita Malanchini   +6 more
wiley   +1 more source

Large-scale genome-wide SNP analysis reveals the rugged (and ragged) landscape of global ancestry, phylogeny, and demographic history in chicken breeds. [PDF]

J Zhejiang Univ Sci B
Dementieva NV, Shcherbakov YS, Stanishevskaya OI, Vakhrameev AB, Larkina TA, Dysin AP, Nikolaeva OA, Ryabova AE, Azovtseva AI, Mitrofanova OV, Peglivanyan GK, Reinbach NR, Griffin DK, Romanov MN.   +13 more
europepmc   +1 more source

Shared genetics between ADHD and reading/language abilities: Genome‐wide correlations, stratified enrichment, cross‐trait association, and mendelian randomization

JCPP Advances, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) and language/reading difficulties frequently co‐occur. The extent of shared genetic architecture remains incompletely defined. We investigated genome‐wide overlap between ADHD and four core skills: word reading, nonword reading, spelling, and phoneme awareness.
Jinzhu Zhao, Shi Huang, Wei Liu, Feng Wang, Hong Qian, Xiaolin Hu   +5 more
wiley   +1 more source

Multivariate genetic analyses test for the presence of a general ‘n’ factor underlying neurodevelopmental conditions

JCPP Advances, EarlyView.
Abstract Background Neurodevelopmental conditions often emerge early in life and have substantial genetic influences. There are significant genetic correlations between neurodevelopmental conditions, such as between autism spectrum disorder (Autism) and attention deficit‐hyperactivity disorder (ADHD), and they are listed together in diagnostic manuals.
Morgan James Morgan, Margherita Malanchini, Elise B. Robinson, Angelica Ronald   +3 more
wiley   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

Journal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang, Zhentao Zhou, Lirong Zhu, Wei Liu   +3 more
wiley   +1 more source

Genome-wide association analysis of resistance to scald in an adapted multiparent winter malting barley population. [PDF]

Plant Genome
Kolkman JM, Sepp SS, Kunze K, Bergstrom GC, Sorrells ME.   +4 more
europepmc   +1 more source

Organic Matter Quality and Microbial Activity in Soils Managed With Brachiaria Succession

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background Although succession systems and brachiaria improve soil quality, gaps remain in microbial community dynamics, activity, and soil organic matter stocks. Methods The objective was to evaluate the carbon (C) and nitrogen (N) stocks of soil organic matter fractions and their distribution, molecular characterization, enzyme activity ...
Siro Paulo Moreira, Vanessa Maria de Souza Barros, David Gabriel Campos Pereira, Humberto Josué de Oliveira Ramos, Eric Batista Ferreira, Teogenes Senna de Oliveira   +5 more
wiley   +1 more source

Development and deployment of a public mid-density genotyping panel for crimson clover (Trifolium incarnatum L.) based on whole-genome re-sequencing of diverse germplasm. [PDF]

Plant Genome
Castillo MP, Oyebode OG, Talag J, Bunting V, Kaur N, Doran P, Barry K, Competti D, Schmutz J, Schlautman B, Humphries A, Ghamkhar K, Moore V, Rios E, Harkess A, Wolfe M.   +15 more
europepmc   +1 more source

Genetic Diversity and Structure Analysis of Wild Oysters (<i>Crassostrea virginica</i>) Within and Between River Systems Reveals Spatial Genetic Structure and Salinity-Adaptive Variation Across the Canadian Maritimes. [PDF]

Evol Appl
Hall S, Méthé D, Steeves R, LaFlamme M, Dinn C, Sonier R, Clements JC.   +6 more
europepmc   +1 more source