Results 241 to 250 of about 1,566,477 (261)

Analyzing Cancer Samples with SNP Arrays

2011
Single nucleotide polymorphism (SNP) arrays are powerful tools to delineate genomic aberrations in cancer genomes. However, the analysis of these SNP array data of cancer samples is complicated by three phenomena: (a) aneuploidy: due to massive aberrations, the total DNA content of a cancer cell can differ significantly from its normal two copies; (b ...
Peter Van Loo, Peter Van Loo, Ole Christian Lingjærde, Vessela N. Kristensen, Vessela N. Kristensen, Vessela N. Kristensen, Anne Lise Børresen-Dale, Anne Lise Børresen-Dale, Silje H. Nordgard, Gro Nilsen, Hans Kristian Moen Vollan, Hans Kristian Moen Vollan   +11 more
openaire   +3 more sources

SNP Arrays for Species Identification in Salmonids

2016
The use of SNP genotyping microarrays, developed in one species to analyze a closely related species for which genomic sequence information is scarce, enables the rapid development of a genomic resource (SNP information) without the need to develop new species-specific markers.
Sigbjørn Lien, Roman Wenne, Kristil Kindem Sundsaasen, Matthew Peter Kent, Agata Drywa   +4 more
openaire   +3 more sources

Copy Number and SNP Arrays in Clinical Diagnostics

Annual Review of Genomics and Human Genetics, 2011
The ability of chromosome microarray analysis (CMA) to detect submicroscopic genetic abnormalities has revolutionized the clinical diagnostic approach to individuals with intellectual disability, neurobehavioral phenotypes, and congenital malformations.
Joanna Wiszniewska, Christian P. Schaaf, Arthur L. Beaudet   +2 more
openaire   +3 more sources

Inferences of genetic architecture of bill morphology in house sparrow using a high‐density SNP array point to a polygenic basis

Molecular Ecology, 2018
Understanding the genetic architecture of quantitative traits can provide insights into the mechanisms driving phenotypic evolution. Bill morphology is an ecologically important and phenotypically variable trait, which is highly heritable and closely ...
Sarah L Lundregan, Ingerid J. Hagen, J. Gohli, A. Niskanen, P. Kemppainen, T. Ringsby, Thomas Kvalnes, H. Pärn, Bernt Rønning, H. Holand, P. Ranke, A. S. Båtnes, L. Selvik, S. Lien, B. Saether, A. Husby, H. Jensen   +16 more
semanticscholar   +1 more source

Array-CGH and SNP-Arrays, the New Karyotype [PDF]

, 2012
Array-comparative genomic hybridisation (array-CGH) and single nucleotide polymorphism array hybridisation (SNP-array) enable genome-wide detection of copy number alterations (CNA). These techniques outperform conventional chromosomal karyotyping in relation to detection of CNAs.
openaire   +1 more source

Correction of database SNP accession numbers misassigned to SNPs of the 8K IRSC apple SNP array

Tree Genetics & Genomes, 2021
Accurate SNP locus identifiers are essential for the correct matching and aggregation of multiple historical datasets. The National Center for Biotechnology Information (NCBI) issued unique “submitted SNP identification” numbers (ssIDs) for every published SNP submitted to its database.
Daniel A. Edge-Garza, Miguel Villamil-Castro, Dorrie Main, Craig Hardner   +3 more
openaire   +2 more sources

High-throughput SNP genotyping on universal bead arrays [PDF]

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2005
We have developed a flexible, accurate and highly multiplexed SNP genotyping assay for high-throughput genetic analysis of large populations on a bead array platform. The novel genotyping system combines high assay conversion rate and data quality with >1500 multiplexing, and Array of Arrays formats.
Arnold Oliphant, Richard Shen, Kevin L. Gunderson, Jian-Bing Fan, Frank J. Steemers, Dennis Doucet, Celeste McBride, Weihua Chang, Jo Yeakley, Eliza Wickham Garcia, Francisco Garcia, Jing Chen, Marina Bibikova, Bahram Ghaffarzadeh Kermani, Derek Campbell   +14 more
openaire   +2 more sources

GenoBaits Soy40K: a highly flexible and low-cost SNP array for soybean studies

Science China Life Sciences, 2022
Yucheng Liu, Shulin Liu, Zhifang Zhang, Lingbin Ni, Xingming Chen, Yunxia Ge, Guo-an Zhou, Zhixi Tian   +7 more
semanticscholar   +1 more source

Universal Tag Arrays in Forensic SNP Analysis

2004
Microarray-based single nucleotide polymorphism (SNP) genotyping enables simultaneous and rapid detection of a large number of markers and is thus an attractive method for forensic individual acid identification. This assay relies on a one-color detection system and minisequencing in solution before hybridization to universal tag arrays.
Anna-Maria Divne, Marie Allen
openaire   +3 more sources

Contribution of SNP arrays in diagnosis of deletion 2p11.2–p12

Gene, 2012
Deletions of the short arm of chromosome 2 are exceedingly rare, having been reported in few patients. Furthermore most cases with deletion in 2p11.2-p12 have been studied using standard karyotype and so it is not possible to delineate the precise size of deletions.
Rocca, Maria Santa, Fabretto, Antonella, Faletra, Flavio, Carlet, Ombretta, Skabar, Aldo, Gasparini, Paolo, Pecile, Vanna   +6 more
openaire   +4 more sources