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Array-CGH and SNP-Arrays, the New Karyotype

2012
Array-comparative genomic hybridisation (array-CGH) and single nucleotide polymorphism array hybridisation (SNP-array) enable genome-wide detection of copy number alterations (CNA). These techniques outperform conventional chromosomal karyotyping in relation to detection of CNAs.
openaire   +1 more source

SNPs on Chips: The Hidden Genetic Code in Expression Arrays

Biological Psychiatry, 2007
Gene expression microarray analysis in postmortem brains is one of the fastest growing fields of psychiatric research. Here we show that common polymorphisms (SNPs) present on probe sets can masquerade as significant "gene expression" differences. After first observing this artifact in the Catechol-O-methyl transferase (COMT) gene, we replicate the ...
Elzbieta, Sliwerska   +7 more
openaire   +2 more sources

High-throughput SNP genotyping on universal bead arrays

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005
We have developed a flexible, accurate and highly multiplexed SNP genotyping assay for high-throughput genetic analysis of large populations on a bead array platform. The novel genotyping system combines high assay conversion rate and data quality with >1500 multiplexing, and Array of Arrays formats.
Richard, Shen   +14 more
openaire   +2 more sources

Microsphere suspension array technology for SNP detection in cattle

IEEE Engineering in Medicine and Biology Magazine, 2003
The genetic improvement of livestock species is a very effective and sustainable method for enhancing the quality of livestock and their products. Selective breeding can be used to induce genetic changes that are both permanent and cumulative. Gene marker tests are now being used by seed stock and commercial cattle breeders to identify the specific ...
Sherry, Dunbar   +3 more
openaire   +2 more sources

Design of Tag SNP Whole Genome Genotyping Arrays

2009
Whole genome association studies have recently been enabled by combining tag SNP information derived from the International HapMap project with novel whole genome genotyping array technologies. In particular, Infinium whole genome genotyping (WGG) technology now has the power to genotype over 1 million SNPs on a single array.
Daniel A, Peiffer, Kevin L, Gunderson
openaire   +2 more sources

Use of SNP-Arrays for ChIP Assays: Computational Aspects

2009
The simultaneous genotyping of thousands of single nucleotide polymorphisms (SNPs) in a genome using SNP-Arrays is a very important tool that is revolutionizing genetics and molecular biology. We expanded the utility of this technique by using it following chromatin immunoprecipitation (ChIP) to assess the multiple genomic locations protected by a ...
Enrique M, Muro   +3 more
openaire   +2 more sources

SNP array technology: an array of hope in breast cancer research.

The Malaysian journal of pathology, 2013
Breast cancer is the most common malignancy in women worldwide. The incidence of breast cancer in Malaysia is lower compared to international statistics, with peak occurrence in the age group between 50 to 59 years of age and mortality rates of 18.6%.
C C, Ho, K S, Mun, R, Naidu
openaire   +1 more source

Development and evaluation of liquid SNP array for large yellow croaker ()

Aquaculture, 2023
Baohua Chen, Qiaozhen Ke, Fei Pu
exaly  

Design and evaluation of a custom 50K Infinium SNP array for egg-type chickens

Poultry Science, 2021
Ning Yang, Congjiao Sun, Guiqin Wu
exaly  

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