Results 1 to 10 of about 77,250 (161)

SAQC: SNP Array Quality Control [PDF]

BMC Bioinformatics, 2011
Background Genome-wide single-nucleotide polymorphism (SNP) arrays containing hundreds of thousands of SNPs from the human genome have proven useful for studying important human genome questions.
Li Ling-Hui, Lin Chien-Wei, Chen Chun-Houh, Kang Meijyh, Lin Hsin-Chi, Yang Hsin-Chou, Wu Jer-Yuarn, Chen Yuan-Tsong, Pan Wen-Harn   +8 more
doaj   +4 more sources

Clinical Utility of SNP Array Analysis in Prenatal Diagnosis: A Cohort Study of 5000 Pregnancies

Frontiers in Genetics, 2020
BackgroundSingle nucleotide polymorphism array (SNP-array) has been introduced for prenatal diagnosis. We aimed to evaluate the clinical value of SNP-array in the diagnosis of fetal chromosomal anomalies.MethodsA retrospective study was conducted on 5000
Jingjing Xiang, Jingjing Xiang, Yang Ding, Yang Ding, Xiaoyan Song, Xiaoyan Song, Jun Mao, Jun Mao, Minjuan Liu, Minjuan Liu, Yinghua Liu, Yinghua Liu, Chao Huang, Chao Huang, Qin Zhang, Qin Zhang, Ting Wang, Ting Wang   +17 more
doaj   +3 more sources

Development and validation of high-density SNP array for genomic studies in Indian yak populations [PDF]

BMC Genomic Data
Background Yaks are multipurpose ruminants crucial for milk, meat, wool, fuel, and high-altitude transportation. Effective management of their genetic resources requires detailed knowledge of their genetic diversity, population structure, and ...
Amod Kumar, Mahesh Dige, Reena Arora, Saket Kumar Niranjan, Sonika Ahlawat, Rekha Sharma, Aneet Kour, Sheikh Firdous Ahmad, K. N. Raja, Karan Veer Singh, Upasna Sharma, Meenal Raheja, Anita Kumari Garsa, Vandana Dureja, Mehak Maggon, Seema Yadav, Kanika Popli, Ramesh Kumar Vijh   +17 more
doaj   +2 more sources

Genetic Relatedness and Heterotic Grouping in MRIZP Elite Maize Inbred Lines Using SNP Markers from 25k SNP Array and RNA-seq Data [PDF]

Current Issues in Molecular Biology
Knowledge of population structure and genetic relationship among inbred lines is essential for exploiting heterosis in maize breeding programs. This study evaluated the concordance between 25k Illumina® Infinum Maize SNP (Single Nucleotide Polymorphism ...
Marko Mladenović, Bojana Banović Đeri, Ana Nikolić, Dragana Dudić, Slaven Prodanović, Sanja Z. Perić, Nikola Grčić   +6 more
doaj   +2 more sources

Evaluation and management of DMD gene copy number variations detected by prenatal SNP-array testing [PDF]

BMC Medical Genomics
Objective This study aims to evaluate the clinical management of incidental findings of copy number variations (CNVs) in the DMD gene detected through prenatal single nucleotide polymorphism array (SNP-array).
Jiancheng Hu, Jialun Pang, Rong Hu, Lin Zhou, Wenxian Yu, Hui Xi, Yingchun Luo, Shuting Yang, Wanglan Tang, Ai Hu, Jing Chen, Ying Peng   +11 more
doaj   +2 more sources

Evaluating Translocation Gene Fusions by SNP Array Data [PDF]

Cancer Informatics, 2011
Somatic cell genetic alterations are a hallmark of tumor development and progression. Although various technologies have been developed and utilized to identify genetic aberrations, identifying genetic translocations at the chromosomal level is still a challenging task.
Hong Liu, Asher Zilberstein, Pascal Pannier, Frederic Fleche, Christopher Arendt, Christoph Lengauer, Chang S. Hahn   +6 more
doaj   +4 more sources

Fine-scale assessment of ROH patterns and genomic inbreeding in diverse horse breeds using two SNP array densities [PDF]

BMC Veterinary Research
Background Inbreeding is caused by mating between related individuals and is associated with reduced fitness and performance. Generally, in the horse population, inbreeding is caused by geographically restricted areas and intensive natural or artificial ...
Moslem Moghbeli Damane, Ahmad Ayatollahi Mehrgardi, Ali Esmailizadeh, Mehdi Momen   +3 more
doaj   +2 more sources

Accuracy of genotype imputation of a low-density SNP array for the Amazon fish Colossoma macropomum [PDF]

Genetics and Molecular Biology
In South America, Tambaqui (Colossoma macropomum) stands as the primary target for aquaculture, yet breeding programs for this Amazon native species are in their early stages. While high-density single nucleotide polymorphism (SNP) arrays are pivotal for
John F. G. Agudelo, Vito A. Mastrochirico-Filho, Baltasar F. Garcia, Raquel B. Ariede, José M. Yáñez, Gustavo M. R. Valladão, Diogo T. Hashimoto   +6 more
doaj   +2 more sources

Assessing the clinical application value of SNP-array in fetal central nervous system malformations [PDF]

Human Genomics
Background Single nucleotide polymorphism array (SNP-array) has been introduced for prenatal diagnosis. This study aims to evaluate the clinical utility of SNP-array in the prenatal central nervous system (CNS) malformations.
Wei Li, Jiasun Su, Weiliang Lu, Xianglian Tang, Chaofan Zhou, Yueyun Lan, Yuan Wei, Limei Huang, Jingrong Luo, Shan Ou, Shuyin Tan, Shengkai Wei, Yaoyao Jiang, Jingyu Su, Liang Wang, Minpan Huang, Jingsi Luo, Peng Huang   +17 more
doaj   +2 more sources

TAFFYS: An Integrated Tool for Comprehensive Analysis of Genomic Aberrations in Tumor Samples. [PDF]

PLoS ONE, 2015
Tumor single nucleotide polymorphism (SNP) array is a common platform for investigating the cancer genomic aberration and the functionally important altered genes.
Yuanning Liu, Ao Li, Huanqing Feng, Minghui Wang   +3 more
doaj   +1 more source