Results 41 to 50 of about 75,225 (256)

Development and Evaluation of a High-Throughput Single-Nucleotide Polymorphism Array for Large Yellow Croaker (Larimichthys crocea)

Frontiers in Genetics, 2020
High-density single-nucleotide polymorphism (SNP) genotyping array is an essential tool for genetic analyses of animals and plants. Large yellow croaker (Larimichthys crocea) is one of the most commercially important marine fish species in China ...
Tao Zhou, Baohua Chen, Qiaozhen Ke, Qiaozhen Ke, Ji Zhao, Fei Pu, Yidi Wu, Lin Chen, Zhixiong Zhou, Yulin Bai, Ying Pan, Ying Pan, Jie Gong, Weiqiang Zheng, Peng Xu, Peng Xu   +15 more
doaj   +1 more source

Clinical Utility and the Yield of Single Nucleotide Polymorphism Array in Prenatal Diagnosis of Fetal Central Nervous System Abnormalities

Frontiers in Molecular Biosciences, 2021
Applying single nucleotide polymorphism (SNP) array to identify the etiology of fetal central nervous system (CNS) abnormality, and exploring its association with chromosomal abnormalities, copy number variations, and obstetrical outcome.
Meiying Cai, Hailong Huang, Liangpu Xu, Na Lin   +3 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Development and application of a 1K functional liquid chip for lactation performance in Bactrian camels

Frontiers in Veterinary Science
IntroductionThe advancement of high-throughput, high-quality, flexible, and cost-effective genotyping platforms is crucial for the progress of dairy breeding in Bactrian camels.
Lili Guo, Lili Guo, Lili Guo, Lema Dao, Bin Liu, Jingyu Wang, Zaixia Liu, Zaixia Liu, Fengying Ma, Fengying Ma, Bielige Morigen, Chencheng Chang, Chencheng Chang, Yinbatu Bai, Yinbatu Bai, Yaqiang Guo, Yaqiang Guo, Caixia Shi, Caixia Shi, Junwei Cao, Junwei Cao, Wenguang Zhang, Wenguang Zhang, Wenguang Zhang   +23 more
doaj   +1 more source

Development of a next generation SNP genotyping array for wheat

Plant Biotechnology Journal, 2023
Summary High‐throughput genotyping arrays have provided a cost‐effective, reliable and interoperable system for genotyping hexaploid wheat and its relatives. Existing, highly cited arrays including our 35K Wheat Breeder's array and the Illumina 90K array were designed based on a limited amount of varietal sequence
Amanda J. Burridge, Mark Winfield, Alexandra Przewieslik-Allen, Keith J. Edwards, Imteaz Siddique, Ruth Barral-Arca, Simon Griffiths, Shifeng Cheng, Zejian Huang, Cong Feng, Susanne Dreisigacker, Alison R. Bentley, Gina Brown-Guedira, Gary L. Barker   +13 more
openaire   +3 more sources

Enhanced Terahertz Thermoelectricity Via Engineered Van Hove Singularities and Nernst Effect in Moiré Superlattices

Advanced Functional Materials, EarlyView.
Moiré band engineering in graphene/hexagonal boron nitride–based superlattices unlocks van Hove singularities (VHSs) for terahertz (THz) optoelectronics. Tuning the Fermi level near these singularities, associated with secondary neutrality points (SNPs), enhances the photothermoelectric response.
Leonid Elesin, Arthur L. Shilov, Subhajit Jana, Ilya Mazurenko, Pierre A. Pantaleon, Mikhail Kashchenko, Nikita Krivovichev, Viacheslav Dremov, Igor Gayduchenko, Takashi Taniguchi, Kenji Watanabe, Yibo Wang, Kostya S. Novoselov, Dmitry A. Svintsov, Grigory Goltsman, Elena I. Titova, Denis A. Bandurin   +16 more
wiley   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

Clinical application of single nucleotide polymorphism array in prenatal diagnosis: Experience with 8753 samples.

PLoS ONE
BackgroundSingle nucleotide polymorphism (SNP) array has been applied to prenatal diagnosis. This study aimed to assess the clinical significance of SNP array in diagnosing fetal chromosomal anomalies based on our experience.MethodsA total of 8753 ...
Li Wen, Yanzhen Zhang, Wen Zhang, Aifen Mao, Xiangjuan Li   +4 more
doaj   +1 more source

Suffix Arrays for Spaced-SNP Databases

CoRR, 2014
Single-nucleotide polymorphisms (SNPs) account for most variations between human genomes. We show how, if the genomes in a database differ only by a reasonable number of SNPs and the substrings between those SNPs are unique, then we can store a fast compressed suffix array for that database.
openaire   +2 more sources

Development of SNP‐genotyping arrays in two shellfish species [PDF]

Molecular Ecology Resources, 2014
AbstractUse of SNPs has been favoured due to their abundance in plant and animal genomes, accompanied by the falling cost and rising throughput capacity for detection and genotyping. Here, we present in vitro (obtained from targeted sequencing) and in silico discovery of SNPs, and the design of medium‐throughput genotyping arrays for two oyster species,
S, Lapègue, E, Harrang, S, Heurtebise, E, Flahauw, C, Donnadieu, P, Gayral, M, Ballenghien, L, Genestout, L, Barbotte, R, Mahla, P, Haffray, C, Klopp   +11 more
openaire   +3 more sources