Results 81 to 90 of about 912,126 (302)

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang, Yuan Fang, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula R. Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, Laura Hagerty, Yetrib Hathout, Michael Ziemba, Lauren Morgenroth, Surajit Bhattacharya, Kanneboyina Nagaraju, Jyoti K. Jaiswal, Eric P. Hoffman   +16 more
wiley   +1 more source

Large SNP arrays for genotyping in crop plants

Journal of Biosciences, 2012
Genotyping with large numbers of molecular markers is now an indispensable tool within plant genetics and breeding. Especially through the identification of large numbers of single nucleotide polymorphism (SNP) markers using the novel high-throughput sequencing technologies, it is now possible to reliably identify many thousands of SNPs at many ...
Martin W, Ganal, Andreas, Polley, Eva-Maria, Graner, Joerg, Plieske, Ralf, Wieseke, Hartmut, Luerssen, Gregor, Durstewitz   +6 more
openaire   +2 more sources

Ashkenazi SNP array data hg18

, 2018
Original Ashkenazi SNP array data used in Gladstein and Hammer ...
Ariella Gladstein (5684096)
core   +1 more source

Clinical and Molecular Characterization of 46 Patients With Beckwith–Wiedemann Spectrum and Uniparental Disomy of 11p15

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Beckwith–Wiedemann spectrum (BWSp) is an overgrowth disorder characterized by its main clinical features macrosomia, macroglossia, and abdominal wall defects. BWSp is caused by (epi)genetic chromosome 11p15 alterations with approximately 20%–27% of patients exhibiting mosaic paternal uniparental disomy of chromosome 11p15 (pUPD11p15).
Saskia M. Maas, Peter Lauffer, Niels Vos, Paola Lombardi, Marcel M. A. M. Mannens, Youp Zegers, Laura J. C. M. van Zutven, Aeilko H. S. Zwinderman, Mieke M. van Haelst, Jet Bliek   +9 more
wiley   +1 more source

Molecular methods for differentiating Phragmites australis subspecies and identification of hybrid stands in the Upper Midwestern United States

Applications in Plant Sciences, EarlyView.
Abstract Premise In North America, Phragmites australis (common reed) has drawn a great deal of research attention. Non‐native P. australis subsp. australis is a noxious weed that has locally displaced native P. australis subsp. americanus in some areas.
Nicholas P. Tippery, Daniel J. Larkin, Julia Bohnen, Douglas L. Wendell, Neil O. Anderson, Susan M. Galatowitsch, Marie Abbey, Alan G. Smith, Andrzej K. Noyszewski   +8 more
wiley   +1 more source

Large-scale deployment of a rice 6 K SNP array for genetics and breeding applications

Rice, 2017
Background Fixed arrays of single nucleotide polymorphism (SNP) markers have advantages over reduced representation sequencing in their ease of data analysis, consistently higher call rates, and rapid turnaround times.
Michael J. Thomson, Namrata Singh, Maria S. Dwiyanti, Diane R. Wang, Mark H. Wright, Francisco Agosto Perez, Genevieve DeClerck, Joong Hyoun Chin, Geraldine A. Malitic-Layaoen, Venice Margarette Juanillas, Christine J. Dilla-Ermita, Ramil Mauleon, Tobias Kretzschmar, Susan R. McCouch   +13 more
doaj   +1 more source

Genotype calling in tetraploid species from bi-allelic marker data using mixture models [PDF]

, 2011
Background Automated genotype calling in tetraploid species was until recently not possible, which hampered genetic analysis. Modern genotyping assays often produce two signals, one for each allele of a bi-allelic marker.
Vosman Ben, Gort, G., Gort Gerrit, Voorrips Roeland E, Roeland E Voorrips, Gerrit Gort, Voorrips, R.E., Vosman, B., Ben Vosman   +8 more
core   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

SNP Array as a Tool for Prenatal Diagnosis of Congenital Heart Disease Screened by Echocardiography: Implications for Precision Assessment of Fetal Prognosis

Risk Management and Healthcare Policy, 2021
Hailong Huang,1,2,* Meiying Cai,1,2,* Yan Wang,1,2 Bin Liang,1,2 Na Lin,1,2 Liangpu Xu1,2 1Center for Prenatal Diagnosis, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, People&
Huang H, Cai M, Wang Y, Liang B, Lin N, Xu L   +5 more
doaj  

SNP-index graph and development of dCAPs marker.

, 2023
(a) SNP-index graph generated by the MutMap analysis of the fon7 gene. Green and orange lines indicate 95% and 99% confidence intervals, respectively. Red regression lines were obtained by averaging SNP indices from a moving window of five consecutive ...
Yoon Kyung Lee (8560953), Phyu Phyu Maung (14333958), Backki Kim (4263070), Su Jang (3706168), Zhuo Jin (6458966), Hee-Jong Koh (45781)   +5 more
core   +1 more source