Results 91 to 100 of about 97,365 (285)
BMC Genomics, 2022 Background Development of large single nucleotide polymorphism (SNP) arrays can make genomic data promptly available for conservation problematic. Medium and high-density panels can be designed with sufficient coverage to offer a genome-wide perspective ...
Alexandra Carrier +14 more
doaj +1 more source
SNP discovery and genotyping using Genotyping-by-Sequencing in Pekin ducks [PDF]
Scientific Reports, 2016 AbstractGenomic selection and genome-wide association studies need thousands to millions of SNPs. However, many non-model species do not have reference chips for detecting variation. Our goal was to develop and validate an inexpensive but effective method for detecting SNP variation. Genotyping by sequencing (GBS) can be a highly efficient strategy for
Zhuo-Cheng Hou, Feng Zhu, Qian-Qian Cui
openaire +2 more sources
AGING MEDICINE, EarlyView.This study employed Mendelian Randomization to assess 1,400 blood metabolites and found a significant inverse association between the glycine‐to‐serine ratio and prostate cancer risk, suggesting a potential causal relationship. ABSTRACT Objectives Metabolic dysregulation is common in cancer, yet evidence linking circulating metabolites to causal ...
Xiaojin Lu +8 more
wiley +1 more source
Candidate gene analysis of femoral neck trabecular and cortical volumetric bone mineral density in older men. [PDF]
, 2010 In contrast to conventional dual-energy X-ray absorptiometry, quantitative computed tomography separately measures trabecular and cortical volumetric bone mineral density (vBMD).
Barrett-Connor, Elizabeth +15 more
core
SNP GENOTYPING IN TETRAPLOID CUT ROSES
Acta Horticulturae, 2012 Genetic analysis in tetraploid rose is complex: inheritance of genes could be disomic, keeping the two original diploid genomes separate but it could also be tetrasomic, permitting the four homologous chromosomes to pair and recombine during meiosis, and including the possibility of double reduction.
Koning-Boucoiran, C.F.S. +4 more
openaire +3 more sources
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey +6 more
wiley +1 more source
Effects of DNA mass on multiple displacement whole genome amplification and genotyping performance
BMC Biotechnology, 2005 Background Whole genome amplification (WGA) promises to eliminate practical molecular genetic analysis limitations associated with genomic DNA (gDNA) quantity.
Haque Kashif A +4 more
doaj +1 more source
High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. [PDF]
, 2015 Human genome-wide association studies have identified thousands of loci associated with disease phenotypes. Genome-wide association studies also have become feasible using rodent models and these have some important advantages over human studies ...
Churchill, Gary A +6 more
core +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Investigations into the etiology and genetic basis of autism continue to drive much autism research, yet reports are emerging of this research not aligning with priorities of autistic people. Engagement of autistic people in the research process is a key way to take their perspectives on board.
Heidi Kristiina Kaljusto +2 more
wiley +1 more source
Multiplex-Ready PCR: A new method for multiplexed SSR and SNP genotyping
BMC Genomics, 2008 Background Microsatellite (SSR) and single nucleotide polymorphism (SNP) markers are widely used in plant breeding and genomic research. Thus, methods to improve the speed and efficiency of SSR and SNP genotyping are highly desirable.
Nguyen Thao M +3 more
doaj +1 more source