Results 111 to 120 of about 337,686 (261)

Combining genotyping approaches improves resolution for association mapping: a case study in tropical maize under water stress conditions

Frontiers in Plant Science
Genome-wide Association Studies (GWAS) identify genome variations related to specific phenotypes using Single Nucleotide Polymorphism (SNP) markers. Genotyping platforms like SNP-Array or sequencing-based techniques (GBS) can genotype samples with many ...
Fernanda Carla Ferreira de Pontes, Ingrid Pinheiro Machado, Maria Valnice de Souza Silveira, Antônio Lucas Aguiar Lobo, Felipe Sabadin, Roberto Fritsche-Neto, Júlio César DoVale   +6 more
doaj   +1 more source

Prim-SNPing: a primer designer for cost-effective SNP genotyping

BioTechniques, 2009
Many kinds of primer design (PD) software tools have been developed, but most of them lack a single nucleotide polymorphism (SNP) genotyping service.
Hsueh-Wei Chang, Li-Yeh Chuang, Yu-Huei Cheng, Yu-Chen Hung, Cheng-Hao Wen, De-Leung Gu, Cheng-Hong Yang   +6 more
doaj   +1 more source

Using the R Package crlmm for Genotyping and Copy Number Estimation [PDF]

Genotyping platforms such as Affymetrix can be used to assess genotype-phenotype as well as copy number-phenotype associations at millions of markers.
Rafael A. Irizarry, Matthew E. Ritchie, Ingo Ruczinski, Robert B. Scharpf, Benilton Carvalho   +4 more
core  

Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joints, bony swelling of the toes and fingers, short stature, kyphosis, and muscle weakness.
Narinder Singh, Arpita Neogi, Liliane H. Gibbs, Jagdish Soni, Elizabeth Chao, Virginia Kimonis   +5 more
wiley   +1 more source

Genotyping-by-sequencing: comparison to SNP chips and whole genome sequencing

, 2015
Outline: Animal Productivity Group; Animal Genomics Team; Genomics Tool Kit; From tissue sample to breeding values; Sheep genome re-sequencing; High Density (HD) SNP Chip development; Genotyping-by-sequencing; GBS-Bioinformatics pipeline; Comparison ...
Rudiger Brauning (47247), Ken Dodds (3501542), Shannon Clarke (3504989), John McEwan (45371), Tracey Van Stijn (10380614)   +4 more
core   +1 more source

How to Use Fewer Markers in Admixture Studies [PDF]

, 2011
Swiss Fleckvieh has been established from 1970 as a composite of Simmental and Red Holstein Friesian cattle. Breed composition is currently reported based on pedigree information. Information on ancestry informative molecular markers potentially provides
Gredler, Birgit, Curik, Ino, Schnyder, Urs, Frkonja, Anamarija, Sölkner, Johann   +4 more
core   +1 more source

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang, Yuan Fang, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula R. Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, Laura Hagerty, Yetrib Hathout, Michael Ziemba, Lauren Morgenroth, Surajit Bhattacharya, Kanneboyina Nagaraju, Jyoti K. Jaiswal, Eric P. Hoffman   +16 more
wiley   +1 more source

Genomic prediction using a cost-effective mid-density SNP platform in spring wheat

Frontiers in Plant Science
Genotyping cost is one of the major limiting factors for wide adoption of genomic selection in wheat. The present study compared two genotyping platforms, a low-density 4K single nucleotide polymorphism (SNP) chip and a Wheat iSelect 90K SNP, in genomic ...
Yaotian Gao, Guriqbal Singh Dhillon, Amandeep Kaur, Pabitra Joshi, Justin Wheeler, Jianli Chen   +5 more
doaj   +1 more source

Model SNP development for complex genomes based on hexaploid oat using high-throughput 454 sequencing technology

BMC Genomics, 2011
Background Genetic markers are pivotal to modern genomics research; however, discovery and genotyping of molecular markers in oat has been hindered by the size and complexity of the genome, and by a scarcity of sequence data.
Chao Shiaoman, Brown Guedira Gina L, Maughan P Jeffrey, Jellen Eric N, Adhikary Dinesh, Wisniewski Morehead Nicole H, Anderson Joseph M, Tinker Nicholas A, Rubenfield Marc J, Lutz Joseph D, Lazo Gerard R, Oliver Rebekah E, Beattie Aaron D, Carson Martin L, Rines Howard W, Obert Donald E, Bonman J Michael, Jackson Eric W   +17 more
doaj   +1 more source

Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips [PDF]

, 2011
The Brassica napus 60K Illumina Infinium™ SNP array has had huge international uptake in the rapeseed community due to the revolutionary speed of acquisition and ease of analysis of this high-throughput genotyping data, particularly when coupled with the
Jensen, CJ, Pender, Michael P., Csurhes, PA, Johnson, LJ, Matthew E Ritchie, Liu, R., Merriman, M, Merriman, T, Danoy, Patrick, Drysdale, K, Brown, Matthew A., Csurhes, Peter A., Greer, Judith M., Guru, P, Liu Ruijie, Wilkins, EJ, Griffiths, Lyn R., Liu, Ruijie, Ritchie, ME, Kermode, AG, Kermode, A.G., Foote, SJ, Carvalho, B.S., Irizarry Rafael A, Hoban, E, Willoughby, E, Butzkueven, H, Ritchie Matthew E, Ritchie, M.E., Rubio, JP, Wiley, J, Cox, MB, Browning, SR, Stankovich, J, Mason, D, Chapman, C, Marriott, M, Tubridy, N, Stewart, GJ, null null, Carvalho, Benilton S., Perera, D, Heard, RN, Polanowski, A, Griffiths, LR, McMorran, BJ, Browning, BL, Ritchie, Matthew E, Clarke, G, Booth, DR, Irizarry, Rafael A., Pryce, Karena, Field, J, Hadler, J, Benilton S Carvalho, Bahlo, M, The Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene), Liu, R, Tajouri, L, Slee, M, Irizarry, RA, Dickinson, JL, Taylor, BV, Lechner-Scott, J, Hadler, Johanna, Kilpatrick, TJ, Greer, JM, Broadley, SA, Pender, MP, Irizarry, R.A., Moscato, P, Perreau, VM, Rafael A Irizarry, Irizarry, Rafael A, Ritchie, Matthew E., Carvalho Benilton S, McCallum, R, Carroll, WM, Scott, RJ, Carvalho, Benilton S, Brown, MA, Whittock, L, Ruijie Liu, Danoy, P, Carvalho, BS, Pryce, K, Broadley, Simon, Stewart, Graeme, Foote, Simon, Jensen, Cathy J, Cox, Mathew B, Bahlo, Melanie, Brown, Matthew A, McMorran, Brendan   +93 more
core   +5 more sources