Results 251 to 260 of about 97,365 (285)

Advancements in ecological niche models for forest adaptation to climate change: a comprehensive review

Biological Reviews, EarlyView.
ABSTRACT Climate change poses significant challenges to the health and functions of forest ecosystems. Ecological niche models have emerged as crucial tools for understanding the impact of climate change on forests at the population, species, and ecosystem levels.
Wenhuan Xu, Dawei Luo, Kate Peterson, Yueru Zhao, Yue Yu, Zhengyang Ye, Jiejie Sun, Ke Yan, Tongli Wang   +8 more
wiley   +1 more source

The C11orf24 Gene as a Useful Biomarker for Predicting Severe Neutropenia in Modified FOLFIRINOX for Pancreatic Cancer

Cancer Science, EarlyView.
FOLFIRINOX improves the prognosis of patients with pancreatic cancer; however, despite UGT1A1 screening, adverse events, such as severe neutropenia, occur frequently. The diagnostic performance of the neutropenia prediction model showed areas under the curve of 0.754 (sensitivity=0.605, specificity=0.848) and 0.856 (sensitivity=0.800, specificity=0.893)
Gen Kanesada, Ryouichi Tsunedomi, Yuki Nakagami, Hiroto Matsui, Yoshitaro Shindo, Shinobu Tomochika, Hirofumi Akita, Tatsuya Ioka, Hidenori Takahashi, Hiroaki Nagano   +9 more
wiley   +1 more source

Diversity of U1 Small Nuclear RNAs and Diagnostic Methods for Their Mutations

Cancer Science, EarlyView.
Complex interindividual U1 snRNA diversity was unveiled. Mutations in such complex loci were precisely detected with a pangenome graph reference, which enhances the possibility of the human pangenome reference in cancer genomics. ABSTRACT U1 small nuclear RNA (snRNA) mutations are recurrent non‐coding alterations found in various malignancies, yet ...
Takuma Nakashima, Tsubasa Miyauchi, Ryota Takeuchi, Yuriko Sugihara, Yusuke Funakoshi, Fumiharu Ohka, Sachi Maeda, Junko Hirato, Takako Yoshioka, Hajime Okita, Yoshitaka Narita, Yonehiro Kanemura, Yasuhiro Kojima, Yuko Watanabe, Ryuta Saito, Hiromichi Suzuki   +15 more
wiley   +1 more source

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Techniques patents for SNP genotyping

Pharmacogenomics, 2003
Single nucleotide polymorphisms (SNPs) are the most abundant form of genetic variation in the human genome, accounting for more than 90% of all differences between individuals. Many complex phenotypes in humans have a significant genetic component and most of the variability is therefore likely to stem from differences in patterns of SNPs.
Richard M. Twyman, Sandy B. Primrose
openaire   +3 more sources

Amplifluor-Based SNP Genotyping

2023
Amplifluor, a genotyping system used to analyze single nucleotide polymorphisms (SNPs), is supplied by Merck-Millipore. Amplifluor is based on polymerase chain reaction (PCR) with two competing allele-specific primers and a SNP specific common reverse primer.
Manmode Darpan, Mohanrao, Senapathy, Senthilvel, Yarabapani Rushwanth, Reddy, Chippa Anil, Kumar, Palchamy, Kadirvel   +4 more
openaire   +2 more sources

Pyrosequencing for SNP Genotyping

2009
Pyrosequencing is a real-time DNA sequencing method. It is based on the transformation of pyrophosphates, released during DNA elongation by DNA polymerase, into measurable light. During DNA elongation, a single pyrophosphate molecule is released following incorporation of a single nucleotide.
Jose Luis Royo, José Jorge Galán
openaire   +3 more sources

Genotyping SNPs With the LightCycler

2004
Here, a single nucleotide polymorphism typing methodology is described based on polymerase chain reaction monitoring, in real time, of fluorescently labeled amplified products using the LightCycler. The main advantages of the system are the time required for the analysis (about 20 min), combined with the robustness, accuracy, and the sensitivity of the
Maria Victoria Lareu, Clara Ruiz-Ponte
openaire   +3 more sources

A New SNP Genotyping Technology by Target SNP-Seq

2023
In order to promote the widespread application of single-nucleotide polymorphism (SNP)-based genotyping, a new method was developed and called target SNP-seq which combined the advantages of multiplex polymerase chain reaction (PCR) amplification and high throughput sequencing on Illumina X Ten platform.
Jian, Zhang, Jingjing, Yang, Changlong, Wen   +2 more
openaire   +2 more sources

SNP Genotyping by Heteroduplex Analysis

2014
Heteroduplex-based genotyping methods have proven to be technologically effective and economically efficient for low- to medium-range throughput single-nucleotide polymorphism (SNP) determination. In this chapter we describe two protocols that were successfully applied for SNP detection and haplotype analysis of candidate genes in association studies ...
Verónica Viviana Lia, Verónica Viviana Lia, Verónica Viviana Lia, Corina M. Fusari, Corina M. Fusari, Andrea F. Puebla, Norma Paniego, Norma Paniego   +7 more
openaire   +3 more sources

SNP Genotyping Technologies

2013
In the recent years, single nucleotide polymorphism (SNP) markers have emerged as the marker technology of choice for plant genetics and breeding applications. Besides the efficient technologies available for SNP discovery even in complex genomes, one of the main reasons for this is the availability of high-throughput platforms for multiplexed SNP ...
Studer, Bruno, Kölliker, Roland
openaire   +2 more sources