Results 231 to 240 of about 337,686 (261)

Pathogenic/likely pathogenic mutations identified in Vietnamese children diagnosed with autism spectrum disorder using high-resolution SNP genotyping platform. [PDF]

Sci Rep
Bui DT, Ton ANV, Nguyen CTD, Nguyen SH, Tran HK, Nguyen XT, Nguyen HT, Pham GLT, Tran DS, Harrington J, Pham HN, Pham TNV, Cao TA.   +12 more
europepmc   +1 more source

Introgressed Brassica napus × Sinapis alba enhance resistance to the crucifer flea beetle (Phyllotreta cruciferae)

Pest Management Science, EarlyView.
This study demonstrates that Brassica napus lines with Sinapis alba introgressions enhanced resistance against Phyllotreta cruciferae, resulting in reduced feeding damage and improved seedling physiological performance. The introgressed lines showed strong potential as genetic resources for developing more resilient and sustainable canola varieties ...
Aziz Ullah, Altaf Hussain, Vicky Roslinsky, Sally L. Vail, Boyd A. Mori   +4 more
wiley   +1 more source

Target‐site mutations and phenotypic failure in Myzus persicae against pyrethroids and carbamates in central Europe

Pest Management Science, EarlyView.
Molecular screening of 140 field‐collected Myzus persicae aphids revealed target‐site mutations L1014F, M918L, M918T, and L932F in the sodium channel and S431F in Ace2. The M918L mutation was the primary driver of high pyrethroid (cypermethrin) resistance, while S431F served as a definitive marker for carbamate (pirimicarb) resistance.
Jitka Stara, Jan Hubert, Pavla Pabiskova, Frantisek Kocourek   +3 more
wiley   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Decreased DMI sensitivity of Plenodomus biglobosus (phoma of oilseed rape) associated with CYP51 substitution G476S

Pest Management Science, EarlyView.
Here, we report for the first time a target site mutation in the CYP51 gene of the oilseed rape phoma stem canker fungus Plenodomus biglobosus (Leptosphaeria biglobosa) that is associated with decreased sensitivity to sterol demethylation inhibitor fungicides.
Kevin M King, Liza M González‐Rodríguez, Joanna Kaczmarek, Małgorzata Jędryczka, Jonathan S West   +4 more
wiley   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Biology, ecology, and conservation of the Italian hare Lepus corsicanus: a review

Wildlife Biology, EarlyView.
The Italian hare Lepus corsicanus, an endemic lagomorph of Italy, serves as a critical case study in evolutionary biology and conservation. Once taxonomically debated, modern genetic and morphological analyses confirm its status as a distinct Pleistocene lineage restricted to the central‐southern Italian Peninsula and Sicily.
Pierangelo Freschi, Valter Trocchi
wiley   +1 more source

Naturally Occurring ZCCHC3 Variants Modulate Antiretroviral Activity in Cynomolgus Macaques

Microbiology and Immunology, EarlyView.
ABSTRACT Many mammalian cells restrict viral replication by utilizing various host restriction factors. We recently demonstrated that CCHC‐type zinc‐finger‐containing protein 3 (ZCCHC3) suppresses human immunodeficiency virus type 1 (HIV‐1) replication through multiple mechanisms.
Jacob Fadipe, Tomotaka Okamura, Shige H. Yoshimura, Akatsuki Saito   +3 more
wiley   +1 more source

Understanding natal emigration in group‐living carnivores

Journal of Animal Ecology, EarlyView.
Dispersal is a key ecological and evolutionary process, yet drivers of variation in emigration under human‐modified conditions remain understudied. Using a novel genetic approach applied to harvested grey wolves in Idaho, USA, we found that prey availability and population density shape natal emigration patterns in a cooperative breeder.
Kathleen M. Petersen, Joel M. Tebbenkamp, Matthew A. Mumma, David E. Ausband   +3 more
wiley   +1 more source

Evidence of parental care as a newly identified reproductive isolating barrier

Journal of Animal Ecology, EarlyView.
Behavioural variation can contribute to reproductive isolation and can be an important driver of speciation. Here, we show that a previously undescribed mechanism, parental care, can function as a postzygotic reproductive isolating barrier when dysregulated in hybrids.
Colby Behrens, Meghan F. Maciejewski, Alexandra Sumarli, Gina Lucas, German Lagunas‐Robles, Kieran Samuk, Alison M. Bell   +6 more
wiley   +1 more source