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2013
In the recent years, single nucleotide polymorphism (SNP) markers have emerged as the marker technology of choice for plant genetics and breeding applications. Besides the efficient technologies available for SNP discovery even in complex genomes, one of the main reasons for this is the availability of high-throughput platforms for multiplexed SNP ...
Studer, Bruno, Kölliker, Roland
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In the recent years, single nucleotide polymorphism (SNP) markers have emerged as the marker technology of choice for plant genetics and breeding applications. Besides the efficient technologies available for SNP discovery even in complex genomes, one of the main reasons for this is the availability of high-throughput platforms for multiplexed SNP ...
Studer, Bruno, Kölliker, Roland
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SNP Genotyping: The KASP Assay
2014The KASP genotyping assay utilizes a unique form of competitive allele-specific PCR combined with a novel, homogeneous, fluorescence-based reporting system for the identification and measurement of genetic variation occurring at the nucleotide level to detect single nucleotide polymorphisms (SNPs) or inserts and deletions (InDels).
Chunlin, He +2 more
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The TaqMan Method for SNP Genotyping
2009Single nucleotide polymorphisms (SNPs) are common DNA sequence variations that occur at single bases within the genome. SNPs have been instrumental in elucidating the genetic basis of common, complex diseases using genome-wide association studies, candidate gene case-control association studies, and genome-wide linkage analyses.
Gong-Qing, Shen +2 more
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SNP marker detection and genotyping in tilapia
Molecular Ecology Resources, 2012AbstractWe have generated a unique resource consisting of nearly 175 000 short contig sequences and 3569 SNP markers from the widely cultured GIFT (Genetically Improved Farmed Tilapia) strain of Nile tilapia (Oreochromis niloticus). In total, 384 SNPs were selected to monitor the wider applicability of the SNPs by genotyping tilapia individuals from ...
van Bers, N.E.M. +4 more
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Isothermal Amplification Methods for the SNP Genotyping
Current Molecular Medicine, 2019The demands for genotyping techniques with acceptable precision, accuracy, cost-effectiveness in high throughput formats made driving forces for continuous development of novel technologies. A wide range of mutation detection techniques based on polymerase chain reaction (PCR) have been introduced.
Somayeh Heidari, Sharafdarkolaee +3 more
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SNP Genotyping with Amplifluor-Like Method
2023For SNP genotyping, amplification of fluorescence (Amplifluor) is a popular and actively developing method in the plant sciences. The "Amplifluor-like" is a "home-made" modification of the original commercial Amplifluor method. Amplifluor-like genotyping requires two essential components: (1) two allele-specific forward primers targeting the SNP site ...
Gulmira, Khassanova +6 more
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Hypertension and SNP Genotyping in Antihypertensive Treatment
Cardiovascular Toxicology, 2005Hypertension is prevalent, affecting approx 20--25% of the adult population in the Western world. Primary hypertension is a multifactorial, complex disorder where many genes and genetic variants are assumed to interact with environmental factors in order to produce the specific blood pressure level for a given individual.
Lisa, Kurland +2 more
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2007
The identification of genes affecting complex traits (i.e., biological traits affected by several genetic and environmental factors) is a very difficult and challenging task (1, 2, 3). For many complex traits, the observable variation between individuals is quantitative; hence, loci affecting such traits are generally termed quantitative trait loci ...
Jun Wang +3 more
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The identification of genes affecting complex traits (i.e., biological traits affected by several genetic and environmental factors) is a very difficult and challenging task (1, 2, 3). For many complex traits, the observable variation between individuals is quantitative; hence, loci affecting such traits are generally termed quantitative trait loci ...
Jun Wang +3 more
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SNP Genotyping Using KASPar Assays
2014In a separate chapter we describe a simple method for single nucleotide polymorphism (SNP) discovery using genomic reduction. Here we describe a scalable and cost-effective SNP genotyping method based on KBioscience's competitive allele-specific PCR amplification of target sequences and endpoint fluorescence genotyping (KASPar™) using a FRET capable ...
Scott M, Smith, Peter J, Maughan
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SNP Genotyping: Technologies and Biomedical Applications
Annual Review of Biomedical Engineering, 2007Single nucleotide polymorphisms (SNPs) are the most frequently occurring genetic variation in the human genome, with the total number of SNPs reported in public SNP databases currently exceeding 9 million. SNPs are important markers in many studies that link sequence variations to phenotypic changes; such studies are expected to advance the ...
Sobin, Kim, Ashish, Misra
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