Results 221 to 230 of about 129,104 (260)
Some of the next articles are maybe not open access.
2007
The identification of genes affecting complex traits (i.e., biological traits affected by several genetic and environmental factors) is a very difficult and challenging task (1, 2, 3). For many complex traits, the observable variation between individuals is quantitative; hence, loci affecting such traits are generally termed quantitative trait loci ...
Jun Wang +3 more
openaire +1 more source
The identification of genes affecting complex traits (i.e., biological traits affected by several genetic and environmental factors) is a very difficult and challenging task (1, 2, 3). For many complex traits, the observable variation between individuals is quantitative; hence, loci affecting such traits are generally termed quantitative trait loci ...
Jun Wang +3 more
openaire +1 more source
Isothermal Amplification Methods for the SNP Genotyping
Current Molecular Medicine, 2019The demands for genotyping techniques with acceptable precision, accuracy, cost-effectiveness in high throughput formats made driving forces for continuous development of novel technologies. A wide range of mutation detection techniques based on polymerase chain reaction (PCR) have been introduced.
Somayeh Heidari, Sharafdarkolaee +3 more
openaire +2 more sources
Hypertension and SNP Genotyping in Antihypertensive Treatment
Cardiovascular Toxicology, 2005Hypertension is prevalent, affecting approx 20--25% of the adult population in the Western world. Primary hypertension is a multifactorial, complex disorder where many genes and genetic variants are assumed to interact with environmental factors in order to produce the specific blood pressure level for a given individual.
Lisa, Kurland +2 more
openaire +2 more sources
SNP Genotyping with Amplifluor-Like Method
2023For SNP genotyping, amplification of fluorescence (Amplifluor) is a popular and actively developing method in the plant sciences. The "Amplifluor-like" is a "home-made" modification of the original commercial Amplifluor method. Amplifluor-like genotyping requires two essential components: (1) two allele-specific forward primers targeting the SNP site ...
Gulmira, Khassanova +6 more
openaire +2 more sources
SNP Genotyping Using KASPar Assays
2014In a separate chapter we describe a simple method for single nucleotide polymorphism (SNP) discovery using genomic reduction. Here we describe a scalable and cost-effective SNP genotyping method based on KBioscience's competitive allele-specific PCR amplification of target sequences and endpoint fluorescence genotyping (KASPar™) using a FRET capable ...
Scott M, Smith, Peter J, Maughan
openaire +2 more sources
SNP Genotyping: Technologies and Biomedical Applications
Annual Review of Biomedical Engineering, 2007Single nucleotide polymorphisms (SNPs) are the most frequently occurring genetic variation in the human genome, with the total number of SNPs reported in public SNP databases currently exceeding 9 million. SNPs are important markers in many studies that link sequence variations to phenotypic changes; such studies are expected to advance the ...
Sobin, Kim, Ashish, Misra
openaire +2 more sources
DNA banks as a resource for SNP genotyping.
2008This chapter provides a brief overview of the current status of DNA Banks, operations at the Australian Plant DNA Bank (www.dnabank.com.au) and sample handling issues relevant to plant genomics research.
Rice, Nicole F +2 more
openaire +4 more sources
A comprehensive evaluation of SNP genotype imputation
Human Genetics, 2008Genome-wide association studies have contributed significantly to the genetic dissection of complex diseases. In order to increase the power of existing marker sets even further, methods have been proposed to predict individual genotypes at un-typed loci from other marker sets by imputation, usually employing HapMap data as a reference.
Michael, Nothnagel +4 more
openaire +2 more sources
High-Throughput Methods for SNP Genotyping
2009Single nucleotide polymorphisms (SNPs) are ideal markers for identifying genes associated with complex diseases for two main reasons. Firstly, SNPs are densely located on the human genome at about one SNP per approximately 500-1,000 base pairs. Secondly, a large number of commercial platforms are available for semiautomated or fully automated SNP ...
Chunming, Ding, Shengnan, Jin
openaire +2 more sources
[Approaches for SNP genotyping].
Yi chuan = Hereditas, 2009With the completion of the Human Genome Project (HGP), typing single nucleotide polymorphisms (SNP) has become one of the main tasks in the post-genome era. Consequently, a robust, flexible and cost-effective technique for SNP typing is essential to analyze a large number of SNPs.
Wei-Peng, Wang +2 more
openaire +1 more source