Results 61 to 70 of about 201,829 (351)
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms [PDF]
, 2017 Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Although 58 genomic regions have been associated with CAD thus far, most of the heritability is unexplained, indicating that additional susceptibility loci await ...
A Schröder +126 more
core +2 more sources
Genomic Analysis Using Bayesian Methods under Different Genotyping Platforms in Korean Duroc Pigs
Animals, 2020 Genomic evaluation has been widely applied to several species using commercial single nucleotide polymorphism (SNP) genotyping platforms. This study investigated the informative genomic regions and the efficiency of genomic prediction by using two ...
Jungjae Lee +9 more
doaj +1 more source
An Empirical Bayes Regression for Multi-tissue eQTL Data Analysis [PDF]
arXiv, 2022 The Genotype-Tissue Expression (GTEx) project collects samples from multiple human tissues to study the relationship between genetic variation or single nucleotide polymorphisms (SNPs) and gene expression in each tissue. However, most existing eQTL analyses only focus on single tissue information.
arxiv
BGT: efficient and flexible genotype query across many samples [PDF]
Bioinformatics, 32: 590-2 (2016), 2015 Summary: BGT is a compact format, a fast command line tool and a simple web application for efficient and convenient query of whole-genome genotypes and frequencies across tens to hundreds of thousands of samples. On real data, it encodes the haplotypes of 32,488 samples across 39.2 million SNPs into a 7.4GB database and decodes a couple of hundred ...
arxiv +1 more source
Genotype imputation accuracy in a F2 pig population using high density and low density SNP panels [PDF]
, 2013 Background: F2 resource populations have been used extensively to map QTL segregating between pig breeds. A limitation associated with the use of these resource populations for fine mapping of QTL is the reduced number of founding individuals and ...
Bates, Ronald O. +5 more
core +1 more source
Genotyping and annotation of Affymetrix SNP arrays
Nucleic Acids Research, 2006 In this paper we develop a new method for genotyping Affymetrix single nucleotide polymorphism (SNP) array. The method is based on (i) using multiple arrays at the same time to determine the genotypes and (ii) a model that relates intensities of individual SNPs to each other.
Carsten Wiuf +4 more
openaire +3 more sources
Population Ecology, EarlyView.In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno +5 more
wiley +1 more source
Frontiers in Plant Science, 2018 Polypoid species play significant roles in agriculture and food production. Many crop species are polyploid, such as potato, wheat, strawberry, and sugarcane.
Qian You +7 more
doaj +1 more source
Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]
, 2020 Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M +7 more
core +2 more sources
Nature, 2003 Extracting useful data from the human genome sequence is a major challenge. Lisa Melton examines the early steps towards personal genotyping.
openaire +2 more sources