Results 91 to 100 of about 423,756 (267)

Depression is associated with CRP SNPs in patients with family history

open access: yesTranslational Neuroscience, 2017
The pathogenesis of depression is not fully understood, but studies have suggested that higher circulating levels of C reactive protein (CRP) might relate to depression occurrence. However, due to the highly variability of individual patients’ conditions,
Yibulaiyin Hasiyeti-   +2 more
doaj   +1 more source

DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women

open access: yesFrontiers in Genetics, 2015
Background: Environmental effects and personal experiences could be expressed in individuals through epigenetic non-structural changes such as DNA methylation. This methylation could up- regulate or down-regulate corresponding gene expressions and modify
Yvon eChagnon   +3 more
doaj   +1 more source

Panel of 32 informative SNPs.

open access: yes, 2015
*These SNPs are reported to break up cluster 1, according to SNP discovery. Major and minor frequencies are based on 177 isolates.** One of Manning, et al. 32 SNPs*** One of Leopold, et al. cluster one SNPs.Panel of 32 informative SNPs.
Molly M. Freeman (763588)   +7 more
core   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

open access: yesAdvanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin   +18 more
wiley   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

open access: yesAdvanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu   +11 more
wiley   +1 more source

ErbB polymorphisms: Insights and implications for response to targeted cancer therapeutics

open access: yesFrontiers in Genetics, 2015
Advances in high-throughput genomic-scanning have expanded the repertory of genetic variations in DNA sequences encoding ErbB tyrosine kinase receptors in humans, including single nucleotide polymorphisms (SNPs), polymorphic repetitive elements ...
Moulay A Alaoui-Jamali   +2 more
doaj   +1 more source

MiRNA-related SNPs and risk of esophageal adenocarcinoma and Barrett's esophagus: Post genome-wide association analysis in the BEACON consortium [PDF]

open access: yes, 2013
Thesis (Master's)--University of Washington, 2013The incidence of esophageal adenocarcinoma (EA) has increased significantly in recent decades. Although several major risk factors have been identified for EA and its precursor, Barrett's esophagus (BE ...
Buas, Matthew Frank
core  

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang   +12 more
wiley   +1 more source

SNPs in protein-coding genes.

open access: yes, 2014
The numbers of nonsynonymous and synonymous SNPs within DIs and outside them, in the comparison of two marine and two freshwater populations (marker SNPs, under the strong criterion) and SNPs within the Nilma marine population.SNPs in protein-coding ...
Aleksey A. Penin (161164)   +7 more
core   +1 more source

Phased SNPs

open access: yes, 2023
SNPs for E. melliodora and E. sideroxylon.Reads were aligned with bwa mem, variants called with bcftools, SNPs phased using WhatsHap & SHAPEIT4.
Scott Ferguson (9952223)
core   +1 more source

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