Results 121 to 130 of about 524,252 (269)

Association of 10 single nucleotide polymorphism loci with nicotine addiction in the Anatolian population?

Biotechnology & Biotechnological Equipment, 2019
The study aimed to discover some variables influencing the risk of nicotine dependence in the Anatolian population. We examined 10 candidate genes and analysed 10 single nucleotide polymorphism (SNP) loci in 50 cases and 50 controls in a preliminary ...
Emel Hulya Yukseloglu, Alpen Ortug, Gulten Rayimoglu, Fatma Cavus Yonar, Itir Erkan, Umut Kara, Dilek Salkim Islek, Melek Ozlem Kolusayin Ozar, Kadir Dastan, Omer Karatas   +9 more
doaj   +1 more source

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

Advanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang, Xuedong Wang, Mengyao Wang, Qian Zhou, Lusheng Wang, Shuai Cheng Li   +5 more
wiley   +1 more source

Editorial: Invasive fungal disease in the immunocompromised host/Research Topic proceedings of the mycology 2021 meeting

Frontiers in Cellular and Infection Microbiology, 2022
Samir Agrawal, Samir Agrawal, Neil Gow, Duncan Wilson, Lewis White   +4 more
doaj   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Genetic Patterns in LDLR Gene Polymorphism among Individuals with Co-Existing Diabetes and Coronary Artery Disease

Medical Journal of Babylon
Background: This research investigates the association between genetic polymorphism in the low-density lipoprotein receptor (LDLR) gene and type 2 diabetes mellitus (T2DM) with coronary artery disease (CAD).
Mohammed Noori Salman, Thekra Abid Jaber Al-Kashwan, Abdulhussein Alwan Faraj Aljanabi   +2 more
doaj   +1 more source

Causal relationship between hepatic function indicators and thrombocytopenia risk in early-stage hepatitis B virus infection: evidence from clinical observational studies and mendelian randomization analyses

Frontiers in Immunology
BackgroundThrombocytopenia is a common occurrence in patients with hepatitis B virus (HBV) infection, particularly in those with liver cirrhosis. However, it can also manifest in the early stages of HBV infection, before the onset of liver cirrhosis ...
Tian-bin Chen, Tian-bin Chen, Jian-wei Jiang, Hong-yan Guo, Xiao-tong Chen, Shuai Zhi, Yu-hai Hu, Ya Fu, Ya Fu, Yong-bing Zeng, Yong-bing Zeng, Can Liu, Can Liu, Qi-shui Ou, Qi-shui Ou, Shi-tao Rao, Shi-tao Rao   +16 more
doaj   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source

Using ddRADseq to assess the genetic diversity of in-farm and gene bank cacao resources in the Baracoa region, eastern Cuba, for use and conservation purposes

Frontiers in Plant Science
The Baracoa region, eastern Cuba, hosts around 80 % of the country cacao (Theobroma cacao L.) plantations. Cacao plants in farms are diverse in origin and propagation, with grafted and hybrid plants being the more common ones.
Angel Rafael Ramirez-Ramirez, Angel Rafael Ramirez-Ramirez, Khaled Mirzaei, Miguel Menéndez-Grenot, Pablo Clapé-Borges, Georgina Espinosa-Lopéz, Igor Bidot-Martínez, Pierre Bertin   +7 more
doaj   +1 more source

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

Advanced Science, EarlyView.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo, Jinxiu Li, Adeniyi C. Adeola, Xueyan Jiang, Juntao Ma, Jian Xiao, Dexiang Hu, Kaixing Qu, Haihong Wu, Junren Chen, Zhanxing He, Tingting Yin, Ali Esmailizadeh, Jing Luo, Olivier Hanotte, Ya‐Ping Zhang, Yan Li   +16 more
wiley   +1 more source