Results 61 to 70 of about 8,567 (186)

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu, Seita Yasuda, Hitoshi Maeshima, Tomoya Ichikawa, Hajime Baba   +4 more
wiley   +1 more source

A systematic review and meta-analysis of randomized controlled head-to-head trials of recommended drugs for neuropathic pain

PAIN Reports
. Neuropathic pain is a challenging chronic pain condition. Limited knowledge exists regarding the relative effectiveness of pharmacological treatments, and differences in trial design and impact of the placebo response preclude indirect comparisons of ...
Ayda Asadizadeh Sadegh, Nina Lykkegaard Gehr, Nanna Brix Finnerup   +2 more
doaj   +1 more source

Channel Capacity of Wavelength Division Multiplexing-Based Brillouin Optical Time Domain Sensors

IEEE Photonics Journal, 2018
We propose and demonstrate a novel WDM-based Brillouin optical time domain analysis (BOTDA) sensor using Brillouin loss configuration, and theoretically analyze channel capacity of WDM-based brillouin optical time domain reflectometry (BOTDR) and BOTDA ...
Zelin Zhang, Yuangang Lu, Yunqin Zhao
doaj   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 3, Page 180-193, April 2026.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source

The relationship of SSRI and SNRI usage with interstitial lung disease and bronchiectasis in an elderly population: a case–control study

Clinical Interventions in Aging, 2017
Ted Rosenberg,1 Rory Lattimer,2 Patrick Montgomery,3 Christian Wiens,4 Liran Levy5 1Department of Family Medicine, University of British Columbia and Island Medical Program, Victoria, BC, 2Home Team Medical Services, Victoria, BC, 3Division of Geriatric
Rosenberg T, Lattimer R, Montgomery P, Wiens C, Levy L   +4 more
doaj  

A Pharmacovigilance Approach for Post-Marketing in Japan Using the Japanese Adverse Drug Event Report (JADER) Database and Association Analysis.

PLoS ONE, 2016
BackgroundRapid dissemination of information regarding adverse drug reactions is a key aspect for improving pharmacovigilance. There is a possibility that unknown adverse drug reactions will become apparent through post-marketing administration ...
Masakazu Fujiwara, Yohei Kawasaki, Hiroshi Yamada   +2 more
doaj   +1 more source

Association of Pregabalin vs. Duloxetine with Cardiovascular Events: A Retrospective Cohort Study Among US Veterans With Chronic Musculoskeletal Pain

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1088-1094, April 2026.
Pregabalin and duloxetine are widely prescribed non‐opioid medications for chronic musculoskeletal pain. Pregabalin may increase the risk of heart failure, and duloxetine increases heart rate and blood pressure; however, little is known about their comparative cardiovascular safety.
Sachalee Campbell, Puran Nepal, Laura Daniel, Otis Wilson, Alyson L. Dickson, Jennifer Maizel, Katherine T. Murray, William D. Dupont, Adriana Hung, Wayne A. Ray, C. Michael Stein, Cecilia P. Chung   +11 more
wiley   +1 more source

Falls and long-term care: a report from the care by design observational cohort study

BMC Family Practice, 2018
Background Falls and the resulting complications are common among frail older adults. We aimed to explore risk factors and potential prevention strategies for falls in elderly residents of Long-Term Care Facilities (LTCF).
Emily J. Cameron, Susan K. Bowles, Emily Gard Marshall, Melissa K. Andrew   +3 more
doaj   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Concomitant use of opioid medications with triptans or serotonergic antidepressants in US office-based physician visits

Drug, Healthcare and Patient Safety, 2018
Kyle C Molina, Kathleen A Fairman, David A Sclar Department of Pharmacy Practice, Midwestern University College of Pharmacy–Glendale, Glendale, AZ, USA Background: Opioids are not recommended for routine treatment of migraine because their benefits
Molina KC, Fairman KA, Sclar DA
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