Results 41 to 50 of about 12,028,240 (312)

Estudio Longitudinal Social de Chile 2016-2022

, 2023
ELSOC has been designed to evaluate how Chileans think, feel, and behave regarding a set of social issues related to conflict and social cohesion in Chile.
Reproducible Research, Centre for Social Conflict and Cohesion Studies COES
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Exploring Intergenerational Educational Mobility in Romania Based on the Intentions of Enrolling in Higher Education Among Upper Secondary Education Students

Sociologie Românească
While education is one of the most important determinants of social position, it remains largely influenced by parental education. Considering the key role of education in the socioeconomic attainment process, this paper explores patterns of ...
Ana-Maria Zamfir, Cristina Mocanu, Raluca Mihaela Molea, Anamaria Năstasă   +3 more
doaj   +1 more source

Effectiveness of an intervention for managing victimization risks related to societal participation for persons with severe mental illness: a cluster RCT study protocol

BMC Psychiatry, 2018
Background People with severe mental illness (SMI) are more likely to experience criminal victimization than other community members. In addition, (self-) stigma and perceived discrimination are highly prevalent in this group.
Wendy M. M. Albers, Diana P. K. Roeg, Yolanda Nijssen, Inge M. B. Bongers, Jaap van Weeghel   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Macroeconomic determinants of labour costs in the EU: a comprehensive panel and cluster analysis

Management şi Marketing
Labour costs are a fundamental component of production expenses, significantly impacting both the quantity and quality of output. This study explores the determinants of labour costs within EU member states that have implemented minimum wage policies ...
Cristescu Amalia, Stănilă Larisa, Vasilescu Maria Denisa, Munteanu Andreea Monica   +3 more
doaj   +1 more source

Recruitment Questionnaire 2024

Pseudonymized survey microdata from the 2024 Recruitment Questionnaire of The Social Study (TSS) — a probability-based panel survey of individuals aged 16+ residing in private households in Belgium.
The Social Study, TSS
core   +1 more source

Editor’s notes : Socio-pedagogical knowledge expertise across the social care sectors in Northern Europe

, 2018
A major challenge in contemporary welfare societies is the delivery of services affirming people’s expectations for their life standard, health and social care services.
Dychawy Rosner, Irena,, Irena Dychawy Rosner, Dychawy Rosner, Irena, Irena, Dychawy Rosner,   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source